Brain Health
Urolithin A Reduces Anxiety by Restoring Brain Mitochondrial Function
Gut metabolite urolithin A dramatically reduced anxiety in rodent models by fixing mitochondrial dysfunction in brain reward circuits.
Research Paper
Mar 29, 2026 1
Results for "Urolithin A" in Alzheimer's
20 articles
Brain Health
Urolithin A Shows Neuroprotective Effects Against Brain Hemorrhage in Mice
Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.
Research Paper
Mar 29, 2026 2
Brain Health
New Alzheimer's Antibody Shows Fewer Blood Vessel Bindings Than Lecanemab
A lab study finds ACU193 binds less to brain blood vessels than lecanemab, potentially explaining differences in ARIA side effect risk.
Research Paper
Jun 3, 2026 0
Brain Health
Single Gene Injection Shields Retinal Cells From Glaucoma Damage
AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.
Research Paper
Jun 22, 2026 0
Brain Health
Declining ULK1 Protein Links Autophagy Failure to Alzheimer's Progression
A master autophagy regulator drops with age and in AD patients โ restoring it in mice clears amyloid, reduces tau, and rescues cognition.
Research Paper
May 15, 2026 0
Brain Health
Restoring Brain Waste Clearance After Stroke by Fixing a Misplaced Water Channel
After ischemic stroke, a mislocated brain water channel (AQP4) disrupts waste clearance. Blocking AQP4 with TGN-020 corrects its position and restores glymphatic flow.
Research Paper
May 12, 2026 0
Brain Health
Natural Compound ฮฑ-Amyrin From Colorful Fruits Protects Against Alzheimer's
AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.
Research Paper
Mar 27, 2026 12
Brain Health
Lithium Shows Promise for Reducing Alzheimer's Brain Plaques and Tau Tangles
Systematic review reveals lithium may slow amyloid buildup and tau protein damage in Alzheimer's disease models.
Research Paper
Mar 28, 2026 2
Brain Health
New Drug Target Shows Promise for Treating Huntington's Disease in Lab Models
Scientists discover blocking UCHL3 enzyme reduces toxic protein clumps and improves cellular cleanup in Huntington's disease models.
Research Paper
Mar 29, 2026 1
Brain Health
Statins May Restore Brain Waste Clearance Disrupted by Alzheimer's Plaques
New research reveals how amyloid-ฮฒ triggers a calcium-cholesterol cascade in brain cells that clogs the glymphatic system โ and how statins may reverse it.
Research Paper
Apr 19, 2026 0
Brain Health
AQP4 Gene Variants Shape Parkinson's Brain Waste Clearance and Motor Decline
Specific AQP4 genetic variants alter glymphatic drainage efficiency, directly influencing motor symptom severity and progression in early Parkinson's disease.
Research Paper
May 16, 2026 0
Brain Health
Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins
New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.
Research Paper
Apr 10, 2026 0
Brain Health
Hidden Proteasome Subtype Clears Parkinson's Toxic Protein and Resists Cellular Blockade
A newly identified proteasome activator, PA200, clears toxic alpha-synuclein aggregates and maintains function even when standard protein-disposal systems fail.
Research Paper
May 29, 2026 0
Brain Health
Herbal Compound Clears Alzheimer's Plaques by Activating AMPK Autophagy Pathway
A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.
Research Paper
May 21, 2026 0
Brain Health
How Kidney Disease Silently Destroys the Brain Through Six Distinct Mechanisms
A major Nature Reviews Nephrology analysis reveals uremic toxins, BBB breakdown, and glymphatic failure drive cognitive decline in CKD patients.
Research Paper
May 12, 2026 0
Brain Health
Blood Tests That Personalize Antidepressants Show Age, BMI, and Kidneys Drive Dosing
A validated UPLC-MS/MS method analyzing 566 plasma samples reveals key patient factors that explain why standard antidepressant doses fail many people.
Research Paper
Jun 22, 2026 0
Brain Health
Blocking TRPV4 Channel Restores Brain Fluid Clearance After Stroke
Inhibiting TRPV4 channels in mice restored glymphatic drainage, cut cerebral edema, and improved neurological recovery after ischemic stroke.
Research Paper
May 13, 2026 0
Brain Health
Glymphatic System Controls Alpha-Synuclein Spread in Parkinson's Disease
New mouse study reveals how the brain's waste-clearance system modulates toxic protein buildup linked to Parkinson's disease.
Research Paper
May 13, 2026 0
Brain Health
Blocking a Brain Stress Protein Clears Alzheimer's Waste and Cuts Amyloid Buildup
Deleting or inhibiting astrocytic PERK restores the brain's glymphatic drainage system and dramatically reduces Aฮฒ and tau pathology in AD mouse models.
Research Paper
May 12, 2026 0
Brain Health
Astrocyte Cholesterol Buildup Blocks Brain Waste Clearance in Alzheimer's
New research links excess astrocytic cholesterol to impaired brain clearance โ a potential key mechanism driving Alzheimer's progression.
Research Paper
May 6, 2026 0
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