Results for "Urolithin A" in Parkinson's

20 articles

Urolithin A Reduces Anxiety by Restoring Brain Mitochondrial Function
Brain Health

Urolithin A Reduces Anxiety by Restoring Brain Mitochondrial Function

Gut metabolite urolithin A dramatically reduced anxiety in rodent models by fixing mitochondrial dysfunction in brain reward circuits.

Research Paper
Mar 29, 2026 1
Urolithin A Shows Neuroprotective Effects Against Brain Hemorrhage in Mice
Brain Health

Urolithin A Shows Neuroprotective Effects Against Brain Hemorrhage in Mice

Pomegranate metabolite urolithin A reduced brain damage and improved recovery in mouse stroke model by blocking inflammation and cell death.

Research Paper
Mar 29, 2026 2
New Alzheimer's Antibody Shows Fewer Blood Vessel Bindings Than Lecanemab
Brain Health

New Alzheimer's Antibody Shows Fewer Blood Vessel Bindings Than Lecanemab

A lab study finds ACU193 binds less to brain blood vessels than lecanemab, potentially explaining differences in ARIA side effect risk.

Research Paper
Jun 3, 2026 0
Single Gene Injection Shields Retinal Cells From Glaucoma Damage
Brain Health

Single Gene Injection Shields Retinal Cells From Glaucoma Damage

AAV delivery of AIBP protein restores cholesterol balance, silences inflammation, and preserves vision in glaucoma models.

Research Paper
Jun 22, 2026 0
Declining ULK1 Protein Links Autophagy Failure to Alzheimer's Progression
Brain Health

Declining ULK1 Protein Links Autophagy Failure to Alzheimer's Progression

A master autophagy regulator drops with age and in AD patients โ€” restoring it in mice clears amyloid, reduces tau, and rescues cognition.

Research Paper
May 15, 2026 0
Alpha-Lipoic Acid Added to Flunarizine Tested for Teen Migraine Prevention
Brain Health

Alpha-Lipoic Acid Added to Flunarizine Tested for Teen Migraine Prevention

A completed Phase 4 trial from India evaluates whether ALA supplementation boosts flunarizine's migraine-prevention power in adolescents.

Clinical Trial
Jun 17, 2026 0
Restoring Brain Waste Clearance After Stroke by Fixing a Misplaced Water Channel
Brain Health

Restoring Brain Waste Clearance After Stroke by Fixing a Misplaced Water Channel

After ischemic stroke, a mislocated brain water channel (AQP4) disrupts waste clearance. Blocking AQP4 with TGN-020 corrects its position and restores glymphatic flow.

Research Paper
May 12, 2026 0
Natural Compound ฮฑ-Amyrin From Colorful Fruits Protects Against Alzheimer's
Brain Health

Natural Compound ฮฑ-Amyrin From Colorful Fruits Protects Against Alzheimer's

AI-driven study identifies ฮฑ-amyrin from fruits and vegetables as a promising Alzheimer's treatment that protects mitochondria and reduces tau tangles.

Research Paper
Mar 27, 2026 12
Lithium Shows Promise for Reducing Alzheimer's Brain Plaques and Tau Tangles
Brain Health

Lithium Shows Promise for Reducing Alzheimer's Brain Plaques and Tau Tangles

Systematic review reveals lithium may slow amyloid buildup and tau protein damage in Alzheimer's disease models.

Research Paper
Mar 28, 2026 2
New Drug Target Shows Promise for Treating Huntington's Disease in Lab Models
Brain Health

New Drug Target Shows Promise for Treating Huntington's Disease in Lab Models

Scientists discover blocking UCHL3 enzyme reduces toxic protein clumps and improves cellular cleanup in Huntington's disease models.

Research Paper
Mar 29, 2026 1
Statins May Restore Brain Waste Clearance Disrupted by Alzheimer's Plaques
Brain Health

Statins May Restore Brain Waste Clearance Disrupted by Alzheimer's Plaques

New research reveals how amyloid-ฮฒ triggers a calcium-cholesterol cascade in brain cells that clogs the glymphatic system โ€” and how statins may reverse it.

Research Paper
Apr 19, 2026 0
FDA Approves First Drug to Treat Neurologic Complications of Hunter Syndrome
Brain Health

FDA Approves First Drug to Treat Neurologic Complications of Hunter Syndrome

Avlayah (tividenofusp alfa-eknm) becomes the first therapy approved to address brain damage in Hunter syndrome, a rare pediatric disorder.

Drug Approval
Apr 28, 2026 0
AQP4 Gene Variants Shape Parkinson's Brain Waste Clearance and Motor Decline
Brain Health

AQP4 Gene Variants Shape Parkinson's Brain Waste Clearance and Motor Decline

Specific AQP4 genetic variants alter glymphatic drainage efficiency, directly influencing motor symptom severity and progression in early Parkinson's disease.

Research Paper
May 16, 2026 0
Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins
Brain Health

Spermine Acts as Molecular Glue to Clear Alzheimer's and Parkinson's Proteins

New research reveals how spermine promotes protein condensation and autophagy to combat neurodegeneration in lab models.

Research Paper
Apr 10, 2026 0
Hidden Proteasome Subtype Clears Parkinson's Toxic Protein and Resists Cellular Blockade
Brain Health

Hidden Proteasome Subtype Clears Parkinson's Toxic Protein and Resists Cellular Blockade

A newly identified proteasome activator, PA200, clears toxic alpha-synuclein aggregates and maintains function even when standard protein-disposal systems fail.

Research Paper
May 29, 2026 0
Herbal Compound Clears Alzheimer's Plaques by Activating AMPK Autophagy Pathway
Brain Health

Herbal Compound Clears Alzheimer's Plaques by Activating AMPK Autophagy Pathway

A traditional Chinese herbal formula improves cognition and cerebrovascular health in Alzheimer's mice by activating the LKB1-AMPK-SIRT1 autophagy cascade.

Research Paper
May 21, 2026 0
Creatine Monohydrate Tested as Bioenergetic Therapy for Alzheimer's Disease
Brain Health

Creatine Monohydrate Tested as Bioenergetic Therapy for Alzheimer's Disease

A completed University of Kansas trial investigates whether creatine monohydrate can support brain energy metabolism in Alzheimer's patients.

Clinical Trial
Jun 18, 2026 0
How Kidney Disease Silently Destroys the Brain Through Six Distinct Mechanisms
Brain Health

How Kidney Disease Silently Destroys the Brain Through Six Distinct Mechanisms

A major Nature Reviews Nephrology analysis reveals uremic toxins, BBB breakdown, and glymphatic failure drive cognitive decline in CKD patients.

Research Paper
May 12, 2026 0
FDA Approves First Drug for Hunter Syndrome Brain Complications in Children
Brain Health

FDA Approves First Drug for Hunter Syndrome Brain Complications in Children

Avlayah becomes the first treatment targeting neurologic symptoms of rare genetic disorder affecting 500 Americans.

Drug Approval
Apr 15, 2026 0
Blood Tests That Personalize Antidepressants Show Age, BMI, and Kidneys Drive Dosing
Brain Health

Blood Tests That Personalize Antidepressants Show Age, BMI, and Kidneys Drive Dosing

A validated UPLC-MS/MS method analyzing 566 plasma samples reveals key patient factors that explain why standard antidepressant doses fail many people.

Research Paper
Jun 22, 2026 0
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