20 articles
Review examines urolithin A's potential as sports supplement, highlighting mitochondrial benefits and safety profile across multiple athletic applications.
Natural compound urolithin A significantly inhibits bone cancer cell migration and invasion through AKT1 and MMP pathway modulation.
Gut metabolite urolithin A enhances mitochondrial quality control through calcium signaling, extending lifespan in worms and protecting human cells.
A deep mechanistic examination of mitophagy's molecular circuitry — from ubiquitin chain topology to mitochondrial-nuclear crosstalk — and the emerging therapeutic strategies targeting this pathway to slow aging.
Go beyond the basics and explore the precise signaling pathways, protein machinery, and regulatory networks that determine which mitochondria live and which get recycled — and why this matters for aging.
Comprehensive review reveals urolithin A's potential to treat neurological disorders by promoting mitophagy and reducing inflammation.
Four-week trial shows mitophagy inducer urolithin A expands youthful T cells and improves immune metabolism in healthy adults aged 45-70.
Review reveals how urolithin A, produced by gut bacteria from dietary tannins, combats obesity via fat browning and metabolism regulation.
Natural compound from pomegranates and berries shows promise for treating cognitive symptoms in Parkinson's disease through brain protection.
Study shows pomegranate compound urolithin A improves motor function in ALS mice by activating cellular cleanup of damaged mitochondria.
Study reveals how urolithin A activates cellular cleanup to reduce dangerous lung inflammation from radiation therapy.
Pomegranate metabolite urolithin A reduces harmful inflammatory signals from aging cells by preventing DNA leakage and blocking cGAS-STING pathway.
Gut metabolite preserves ovarian reserve by blocking harmful signaling pathways and preventing follicle death during cancer treatment.
New research reveals how this pomegranate compound protects lungs during sepsis by restoring cellular powerhouses and reducing inflammation.
Natural compound from berries and nuts prevents tendon cell death and oxidative damage in obesity-related conditions.
New research reveals how a gut microbiome metabolite reduces joint inflammation and cell death in rheumatoid arthritis models.
Study finds urolithin A from pomegranates reduces schizophrenia-like behaviors and cognitive deficits in female rats by targeting brain inflammation.
Study shows urolithin A from pomegranates promotes nerve regeneration by clearing damaged mitochondria and reducing inflammation.
Researchers identify a protective genetic variant that reduces zinc accumulation in kidneys, offering new therapeutic targets for kidney disease.
Researchers identify a new CYP24A1 gene variant causing vitamin D metabolism dysfunction and chronic calcium elevation.
The Break Wave device shatters kidney stones into passable fragments in 7 of 10 patients, no anesthesia needed, in a clinic setting.
Targeting MCL-1 protein during acute kidney injury removes harmful senescent cells and prevents progression to chronic kidney disease.
