Your VO2 Max in Your 70s Could Cut Alzheimer's Risk in Half
Older adults with higher cardiorespiratory fitness had ~48% lower Alzheimer's risk over 8.7 years, with a clear VO2 threshold identified.
20 articles
Older adults with higher cardiorespiratory fitness had ~48% lower Alzheimer's risk over 8.7 years, with a clear VO2 threshold identified.
High-intensity home cycling improved ataxia symptoms, fatigue, and VO2max significantly more than dose-matched balance training over one year.
Excessive vigorous exercise triggers a muscle-derived factor that acts as a mitochondrial imposter, impairing cognitive function.
A machine-learning model using 39 cardiovascular and autonomic variables predicted cognitive test performance with ~71% accuracy in healthy adults.
Large trial of 513 older adults finds exercise and intensive cardiovascular risk reduction don't significantly improve cognitive function.
How you spend your 24 hours — sleeping, sitting, or moving — determines your baseline brain function and exercise responsiveness.
A liver enzyme released during exercise may rejuvenate brain blood vessels and protect against cognitive decline and Alzheimer's pathology.
Nicotinamide riboside prevents moyamoya-like brain vessel blockages by fixing cellular energy production in smooth muscle cells.
Long-term intensive training reshapes hemispheric brain organization in elite athletes, and these changes prove resilient to sport-related concussions.
A randomized pilot study finds PEMF therapy significantly improved fatigue, sleep, depression, and walking capacity in post-COVID-19 patients over 5 weeks.
Simple compound successfully treats life-threatening COQ2 deficiency in newborn, offering hope for rare mitochondrial disorders.
A 4-week pilot trial finds nicotinamide riboside boosts cerebrovascular response and cognitive performance in older adults with peripheral artery disease.
DPCPX treatment enhanced neurogenesis and improved motor/memory function in stroke recovery studies using advanced PET imaging.
Bilateral theta burst stimulation enhanced neural repair and restored function after stroke in non-human primates through multiple mechanisms.
New study reveals brain imaging can identify which people with mild cognitive impairment respond best to targeted interventions.
New research reveals age-specific effects of vagus nerve stimulation on brain activity, with older adults showing stronger responses.
A prospective trial finds 15 days of gamma-frequency tACS improves memory, attention, and executive function in mild Alzheimer's disease.
Randomized trial shows structured breathing exercises improve mental health and resilience in high-stress healthcare training.
A post hoc analysis of the DISTAL trial finds EVT plus medical therapy significantly improves brain tissue preservation in hard-to-reach vessel occlusions.
People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.