20 articles
A meta-analysis of 30 RCTs finds plyometric training delivers significant gains across sprinting, jumping, and endurance metrics in track and field athletes.
A meta-analysis of 10 RCTs finds structured exercise significantly improves quality of life and VO2 max in adults over 50 living with HIV.
Burke and Noakes reach surprising common ground on fueling endurance sport, while key disagreements remain unresolved.
Leading researchers establish best practices for studying exercise benefits in rodents to improve human health translation.
A 30-study review finds exercise and mindfulness alter resting brain connectivity, but the largest rigorous trial shows minimal effects.
New review links physical activity to glymphatic function — the brain's built-in detox network that flushes neurotoxic proteins.
A new narrative review finds IF activates powerful antioxidant pathways, but warns that clinical proof in humans remains thin and short-term.
A new framework reveals how lactate and β-hydroxybutyrate team up across organs to regulate metabolism, mitochondria, and disease.
A meta-analysis of 4,941 adults finds FTO risk-allele carriers have higher triglycerides on calorie-restricted diets, but most metabolic markers respond similarly across genotypes.
A landmark AHA statement challenges decades of blanket activity restrictions for children with cardiomyopathy, offering new risk-stratified guidance.
A systematic review of RCTs finds night fasting windows improve glucose and lipid markers in shift workers, though evidence remains thin.
A new review argues that combining GLP-1 receptor agonists with structured exercise and dietary support preserves muscle and delivers lasting fat loss.
Longevity experts endorse CGMs for metabolic optimization, but RCT evidence in non-diabetics is still thin.
A new review maps how blood stem cell metabolism shifts with aging and how leukemia hijacks those changes — pointing to targeted therapeutic strategies.
Expert reviews of top CGM platforms reveal genuine metabolic insights — but no proof they extend lifespan in healthy adults.
A new review reframes magnesium as a master regulator of mitochondrial energy, metabolic disease, and biological aging.
A Cochrane meta-analysis of 8 RCTs finds most pharmacological treatments fail to improve ataxia scores, though upper limb dexterity may benefit.
A comparative review of NMN and NR supplements weighs tissue targeting, clinical evidence, and top-rated products for NAD+ optimization.
A head-to-head review of 10 CGM devices for healthy adults, weighing real-world accuracy data against limited longevity evidence.
A Circulation review from Harvard proposes the 'target trial framework' to improve how observational data is used to assess cardiovascular device safety and effectiveness.
