20 articles
Neuronal signals fuel small cell lung cancer via the vagus nerve and direct neuron-to-tumor synapses, opening new therapeutic targets.
A Nature study reveals lung tumors activate vagal nerves to drive sympathetic signaling that shuts down anti-tumor immunity.
New research reveals how activating vascular STING pathways helps immune cells infiltrate and destroy aggressive lung cancer cells.
A Nature study reveals neurons physically transfer mitochondria to breast cancer cells via tunneling nanotubes, boosting metastatic potential.
Engineered immune cell vesicles first induce cancer cell senescence with chemo, then eliminate them with targeted senolytic drugs.
Antibody-drug conjugate achieved 21% response rate in heavily pretreated patients with limited options.
Phase I trial shows NT-I7 safely increases lymphocyte counts and expands cancer-fighting T cells in high-grade glioma patients.
Scientists discover IGSF11-VISTA pathway as promising target for deadly childhood brain tumors, offering hope for new treatments.
A phase 1 trial finds intraventricular nivolumab is safe for leptomeningeal metastases, with median survival of 6.6 months.
A phase 1 trial shows Temferon — a gene-engineered stem cell therapy — safely delivers interferon-α into glioblastoma tumors with no dose-limiting toxicities.
Synthetic super-enhancers hijack glioblastoma's own regulatory circuits to trigger precise, tumor-only cell death and durable immune memory.
A phase 2 trial shows rogaratinib produces durable responses in a hard-to-treat GIST subtype driven by epigenetic oncogene activation.
Scientists develop safer way to deliver immune-boosting genes directly to tumors, enhancing radiation therapy effectiveness.
The COMPETE trial shows radioligand therapy extends progression-free survival by nearly 10 months vs. standard targeted therapy in GEP NETs.
A phase 1 trial of a neoantigen DNA vaccine for glioblastoma found strong immune responses and survival rates exceeding historical benchmarks.
New research explores yoga as complementary therapy for painful peripheral neuropathy affecting up to 70% of chemotherapy patients.
A sex-specific GABA signaling pathway supercharges immune suppression in female glioblastoma, revealing a potential new immunotherapy target.
New study shows stereotactic radiotherapy protects cognitive function while treating brain metastases effectively.
New review reveals how neurotransmitters like norepinephrine and acetylcholine directly regulate immune cells in tumors, opening therapeutic targets.
Breakthrough therapy converts tumor cells into antigen-presenting cells that train immune system to destroy cancer.
