Gut Device Outperforms Semaglutide for Weight Loss and Insulin Sensitivity in Animal Study
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
20 articles
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
New research shows ketogenic diet and exercise can reverse peripheral neuropathy caused by metabolic syndrome in mice.
Takeda's Phase 1 trial evaluates the safety and tolerability of TAK-510, a novel injectable agent targeting nausea and vomiting, across escalating doses.
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
275-patient study tests novel liver-targeted therapy for NASH, a serious form of fatty liver disease affecting millions worldwide.
UC Riverside scientists developed a gel that delivers continuous oxygen to chronic wounds, healing fatal injuries in diabetic mice within weeks.
A completed RCT tests whether small-sided football sessions 3x/week improve glucose control and metabolic health in T2DM patients on GLP-1 and SGLT2 drugs.
A 5-year study finds bariatric surgery offers meaningful but attenuated weight loss in PWS kids versus lifestyle intervention alone.
Electromagnetic biomaterials offer breakthrough approach to diabetic wound healing by reducing inflammation and promoting tissue regeneration.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
New research shows chronic semaglutide treatment causes weight loss while leaving taste perception fully intact, pointing to motivational rather than sensory mechanisms.
Maastricht University investigated whether NA, NAM, and tryptophan together could restore mitochondrial function in physically compromised older adults.
411-person study shows digital insulin delivery system helps optimize glucose control through automated dose tracking and mobile integration.
New research reveals which bariatric surgery works best and identifies patient factors that predict long-term success.
Enanta Pharmaceuticals tests its FXR agonist EDP-305 in a completed Phase 2 randomized trial for non-alcoholic steatohepatitis.
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
A completed University of Michigan trial explored how aerobic exercise training alters RAGE-mediated inflammatory pathways in type 2 diabetic adults.
Combined mitochondrial therapy restored muscle function and reduced fatigue in mouse model of Gulf War Illness.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
Wearable microneedle patches tap interstitial fluid to monitor glucose, lactate, and electrolytes in real time — no needles, no lab.