20 articles
A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.
New research shows ketogenic diet and exercise can reverse peripheral neuropathy caused by metabolic syndrome in mice.
New research reveals pulsed electromagnetic field therapy selectively enhances ATP-linked mitochondrial respiration, pointing to a specific cellular energy mechanism.
A 5-year study finds bariatric surgery offers meaningful but attenuated weight loss in PWS kids versus lifestyle intervention alone.
Electromagnetic biomaterials offer breakthrough approach to diabetic wound healing by reducing inflammation and promoting tissue regeneration.
A new ESRRA-ATG5 axis links mitochondrial recycling to arginine metabolism, and a plant polyphenol activates it to protect diabetic kidneys.
New research shows chronic semaglutide treatment causes weight loss while leaving taste perception fully intact, pointing to motivational rather than sensory mechanisms.
New research reveals which bariatric surgery works best and identifies patient factors that predict long-term success.
A landmark JCI review maps the expanding pharmacological arsenal for MASH, from GLP-1 agonists to triple receptor therapies and precision medicine.
Combined mitochondrial therapy restored muscle function and reduced fatigue in mouse model of Gulf War Illness.
New research reveals how blood vessel maturity around transplanted insulin-producing cells determines long-term survival.
Wearable microneedle patches tap interstitial fluid to monitor glucose, lactate, and electrolytes in real time — no needles, no lab.
A dual-action therapy combining a glucose-responsive hydrogel with stem cell exosomes dramatically speeds diabetic wound closure in mice.
Updated review of anti-obesity medications in MASLD finds GLP-1 agonists reduce steatosis and fibrosis, while newer dual/triple agonists show even greater metabolic promise.
Low-intensity resistance training with blood flow restriction improved muscle strength and mitochondrial function better than conventional exercise.
New research validates high-throughput methods for studying mitochondrial dysfunction in malignant hyperthermia susceptibility.
A 60-week RCT finds semaglutide 2.4 mg sustains ~240 kcal/day reduction even after appetite benefits diminish.
Brief weekly PEMF exposures increased quail embryo weight by ~20%, body length by ~15%, and upregulated key oxidative muscle genes.
Emerging evidence suggests GLP-1 receptor agonists like semaglutide may reduce cocaine craving and relapse by dampening dopamine signaling.
Novel GLP-1 analogue NNC5840 achieves greater weight reduction than semaglutide by optimizing receptor signaling bias rather than potency.
