Chemical Reprogramming Causes Toxic Lipid Buildup That Blocks Anti-Aging Effects
New study reveals why promising chemical cocktails for cellular rejuvenation fail in living mice - dangerous fat accumulation.
19 articles
New study reveals why promising chemical cocktails for cellular rejuvenation fail in living mice - dangerous fat accumulation.
Researchers propose using partial reprogramming to rejuvenate donor organs outside the body before transplantation.
Researchers identify methods to induce powerful regenerative cell clusters in mammals using temporary pluripotency factors.
Scientists discover how reprogramming factors rejuvenate eye cells and restore vision by activating a protective enzyme that clears toxic lipids.
Japanese researchers develop minimally invasive method to transform T cells into glutamatergic neurons using just 5 factors.
New research reveals how cellular identity loss accelerates aging and disease, but Yamanaka factors can reverse this process.
New research using extreme value theory suggests human aging may plateau at 110, making lifespan theoretically unlimited but practically short.
Researchers developed a method to artificially age stem cells, creating better models for studying neurodegeneration and other age-related conditions.
New small-molecule approach offers safer alternative to genetic reprogramming for turning back the cellular clock.
New research reveals why stem cells from Alzheimer's patients retain disease signatures that affect brain development.
The father of induced pluripotent stem cells discusses regenerative medicine milestones and future therapeutic potential.
Breakthrough chemical reprogramming method transforms ordinary blood cells into versatile stem cells without genetic modification.