Advanced Therapies

442 articles in this topic

RNA Editing Therapy for AATD Moves Toward Convenient Monthly Dosing
Regenerative Medicine

RNA Editing Therapy for AATD Moves Toward Convenient Monthly Dosing

Wave Life Sciences shares early trial data on an RNA editing treatment for alpha-1 antitrypsin deficiency, targeting monthly dosing.

Press Release
May 20, 2026 0
GLP-1 Drugs Reshape Obesity Treatment as Surgery Declines and New Data Emerges
Longevity & Aging

GLP-1 Drugs Reshape Obesity Treatment as Surgery Declines and New Data Emerges

GLP-1 use surged 140% as bariatric surgery dropped 34%. New findings span creatine for menopause, osteoporosis risk, and obesity trend reversals.

Press Release
May 20, 2026 0
Low-Dose Buprenorphine Boosts Ketamine's Anti-Suicide Effects in Depression
Longevity & Aging

Low-Dose Buprenorphine Boosts Ketamine's Anti-Suicide Effects in Depression

A Stanford trial finds combining buprenorphine with ketamine nearly doubles the reduction in suicidal ideation scores over 31 days.

Press Release
May 20, 2026 0
Omega-3 Supplements Linked to Faster Cognitive Decline in Older Adults
Longevity & Aging

Omega-3 Supplements Linked to Faster Cognitive Decline in Older Adults

New findings challenge omega-3 supplementation for brain health, while sleep and genetics shape Alzheimer's risk in women.

Press Release
May 20, 2026 0
RAS Inhibitors Enter a New Era as Next-Gen Cancer Drugs Advance
Regenerative Medicine

RAS Inhibitors Enter a New Era as Next-Gen Cancer Drugs Advance

A second wave of RAS-targeting therapies is reshaping cancer treatment, with implications for longevity through better tumor control.

Press Release
May 20, 2026 0
One Protein Fights Inflammaging and Made Aging Mice Stronger and Healthier
Longevity & Aging

One Protein Fights Inflammaging and Made Aging Mice Stronger and Healthier

Scientists boosted a protein that dampens chronic inflammation, and older mice grew stronger, more energetic, and had healthier bones.

Press Release
May 20, 2026 0
Senolytic Drug ABT-263 Clears Zombie Cells and Dramatically Speeds Wound Healing in Aged Skin
Longevity & Aging

Senolytic Drug ABT-263 Clears Zombie Cells and Dramatically Speeds Wound Healing in Aged Skin

A topical senolytic drug cleared aging 'zombie' cells from old skin, helping aged mice heal wounds 43% more completely by day 24.

Press Release
May 20, 2026 0
CRISPR Tool Kills Cancer Cells by Reading Their RNA With Surgical Precision
Longevity & Aging

CRISPR Tool Kills Cancer Cells by Reading Their RNA With Surgical Precision

A new Cas12a2-based system identifies cancerous or virus-infected cells by their RNA and destroys them โ€” tested across multiple human cancer lines.

Press Release
May 20, 2026 0
Gene Therapy Breakthrough Delivers Treatment Directly to the Brain
Longevity & Aging

Gene Therapy Breakthrough Delivers Treatment Directly to the Brain

JCR Pharmaceuticals shows its JUST-AAV platform can cross the blood-brain barrier, extending survival in neurological disease mouse models.

Press Release
May 20, 2026 0
AI Designs First Inhaled Drug Candidate to Target Pulmonary Fibrosis
Longevity & Aging

AI Designs First Inhaled Drug Candidate to Target Pulmonary Fibrosis

Insilico Medicine's AI-generated TNIK inhibitor enters Phase 1 trials for pulmonary fibrosis, signaling a new era in drug discovery.

Press Release
May 20, 2026 0
FDA Approves First Aldosterone Synthase Inhibitor BAXFENDY to Tackle Resistant Hypertension
Longevity & Aging

FDA Approves First Aldosterone Synthase Inhibitor BAXFENDY to Tackle Resistant Hypertension

AstraZeneca's BAXFENDY cuts systolic blood pressure by nearly 10 mmHg beyond placebo in adults whose BP wasn't controlled by other drugs.

Press Release
May 20, 2026 0
Gut Bacteria Help Melanoma Patients Respond to Immunotherapy Again
Longevity & Aging

Gut Bacteria Help Melanoma Patients Respond to Immunotherapy Again

A Phase 1b trial shows a daily probiotic capsule may restore immunotherapy response in advanced melanoma patients who had stopped responding.

Press Release
May 20, 2026 0
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