Alzheimer's

444 articles in this topic

ML Pipeline Advances Detection of Age-Related Brain Microbleeds in Mouse Model
Brain Health

ML Pipeline Advances Detection of Age-Related Brain Microbleeds in Mouse Model

Researchers built a machine learning imaging pipeline to detect cerebral microhemorrhages and tested SS-31 (elamipretide) in aged hypertensive mice.

Research Paper
May 20, 2026 0
Wrist Accelerometers Predict Dementia Risk as Well as APOE Gene Testing
Brain Health

Wrist Accelerometers Predict Dementia Risk as Well as APOE Gene Testing

Sleep-wake patterns measured by wearables significantly predict dementia risk in 57,000+ older adults, matching the predictive power of genetic testing.

Research Paper
May 20, 2026 0
Playing Music Stops Uncontrollable Eye Spasms in Rare Neurological Case
Brain Health

Playing Music Stops Uncontrollable Eye Spasms in Rare Neurological Case

A professional oboist discovered that playing her instrument or singing completely suppressed her debilitating blepharospasm symptoms.

Research Paper
May 20, 2026 0
New Statistical Method Could Sharpen Alzheimer's Drug Trial Results
Brain Health

New Statistical Method Could Sharpen Alzheimer's Drug Trial Results

Researchers test a quantile-aggregation approach that may improve how Alzheimer's clinical trials detect treatment effects.

Research Paper
May 20, 2026 0
New Brain Mapping Tool Reveals Microglia Linked to Alzheimer's Plaques
Brain Health

New Brain Mapping Tool Reveals Microglia Linked to Alzheimer's Plaques

A spatial proteomics platform profiled 700,000+ brain cells, identifying a microglial subset that clusters around amyloid-Ξ² plaques in Alzheimer's disease.

Research Paper
May 19, 2026 0
Single MRI Scan Now Predicts Alzheimer's Diagnosis and Future Cognitive Decline
Brain Health

Single MRI Scan Now Predicts Alzheimer's Diagnosis and Future Cognitive Decline

A new deep learning model from UCSF predicts Alzheimer's diagnosis and cognitive trajectories from one MRI scanβ€”no expensive multimodal imaging required.

Research Paper
May 19, 2026 0
Newly Discovered Axonic Spines Rewire How Neurons Fire Action Potentials
Brain Health

Newly Discovered Axonic Spines Rewire How Neurons Fire Action Potentials

A surprising structural feature on axon initial segments lets excitatory synapses jump-start neuron firing and redirect brain circuit information flow.

Research Paper
May 18, 2026 0
Cholesterol Metabolite 27-OHC Accelerates Brain Aging via Microglial Iron Overload
Brain Health

Cholesterol Metabolite 27-OHC Accelerates Brain Aging via Microglial Iron Overload

27-Hydroxycholesterol triggers microglial senescence through iron dysregulation, and the iron chelator deferoxamine reverses the damage.

Research Paper
May 17, 2026 0
Wearable Alcohol Biosensors Are Transforming How Scientists Track Drinking
Brain Health

Wearable Alcohol Biosensors Are Transforming How Scientists Track Drinking

Transdermal alcohol monitors paired with machine learning can now detect drinking events with over 90% accuracy β€” a leap beyond flawed self-reports.

Research Paper
May 17, 2026 0
MCI Patients Show Brain Overactivation and Muscle Dysfunction During Dual Tasking
Brain Health

MCI Patients Show Brain Overactivation and Muscle Dysfunction During Dual Tasking

People with mild cognitive impairment recruit extra brain regions and show altered muscle control just to stay balanced while thinking.

Research Paper
May 17, 2026 0
Cross-Species Brain Scans Reveal Two Distinct Biological Subtypes of Autism
Brain Health

Cross-Species Brain Scans Reveal Two Distinct Biological Subtypes of Autism

Researchers matched fMRI patterns across mouse models and 1,976 humans to find autism splits into hypo- and hyperconnectivity subtypes with distinct biology.

Research Paper
May 17, 2026 0
fMRI Reveals Hidden Brain Subtypes Within Autism Spectrum Disorder
Brain Health

fMRI Reveals Hidden Brain Subtypes Within Autism Spectrum Disorder

New fMRI research from UNC Chapel Hill uncovers distinct neurological subtypes within ASD, potentially reshaping diagnosis and treatment.

Research Paper
May 17, 2026 0
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