Auto-Immunity

15 articles in this topic

UK Trial of Biologics for Refractory Rare Vasculitis Terminated Early
Autoimmune & Arthritis

UK Trial of Biologics for Refractory Rare Vasculitis Terminated Early

A Phase 2 trial testing rituximab, infliximab, and tocilizumab for hard-to-treat non-ANCA vasculitis was terminated before completion.

Clinical Trial
May 20, 2026 0
Couples-Based HIV Prevention Program Tests PrEP Adherence and Stigma Reduction in South Africa
Autoimmune & Arthritis

Couples-Based HIV Prevention Program Tests PrEP Adherence and Stigma Reduction in South Africa

A cluster randomized trial tests whether couples counseling plus stigma workshops can boost PrEP/ART uptake among young South African adults.

Clinical Trial
May 14, 2026 0
Placental Stem Cell Secretome Tested as GvHD Treatment in Phase 3 Trial
Autoimmune & Arthritis

Placental Stem Cell Secretome Tested as GvHD Treatment in Phase 3 Trial

A completed Phase 3 trial tests placental MSC secretome injections against placebo in 60 GvHD patients at an Iranian hospital.

Clinical Trial
May 12, 2026 0
JAK Inhibitor Tofacitinib Shows Promise Against Rheumatoid Arthritis in Phase 3 Trial
Autoimmune & Arthritis

JAK Inhibitor Tofacitinib Shows Promise Against Rheumatoid Arthritis in Phase 3 Trial

Pfizer's oral JAK inhibitor demonstrated efficacy comparable to adalimumab for treating moderate to severe rheumatoid arthritis.

Clinical Trial
Mar 28, 2026 0
Rheumatoid Arthritis Damages Muscle Function Even in Early Disease Stages
Autoimmune & Arthritis

Rheumatoid Arthritis Damages Muscle Function Even in Early Disease Stages

New research reveals how RA affects muscle biomechanics within 6 months of symptom onset, offering insights for early intervention.

Clinical Trial
Mar 28, 2026 0
Real-World Study Compares JAK and TNF Inhibitors for Rheumatoid Arthritis Safety
Autoimmune & Arthritis

Real-World Study Compares JAK and TNF Inhibitors for Rheumatoid Arthritis Safety

Large Hong Kong registry study tracked how well patients stayed on newer JAK inhibitors versus traditional TNF blockers for RA treatment.

Clinical Trial
Mar 28, 2026 0
New JAK3 Inhibitor ZL-82 Shows Promise for Rheumatoid Arthritis Treatment
Autoimmune & Arthritis

New JAK3 Inhibitor ZL-82 Shows Promise for Rheumatoid Arthritis Treatment

Phase I trial tests selective JAK3 inhibitor with improved safety profile compared to existing treatments for inflammatory conditions.

Clinical Trial
Mar 28, 2026 4
JAK Inhibitor Tofacitinib Shows Promise for Lupus Treatment in Safety Trial
Autoimmune & Arthritis

JAK Inhibitor Tofacitinib Shows Promise for Lupus Treatment in Safety Trial

Small NIH study tests oral drug tofacitinib as potential new treatment for systemic lupus erythematosus with fewer side effects.

Clinical Trial
Mar 28, 2026 4
Early Rheumatoid Arthritis Treatment Shows Promise for Rapid Remission
Autoimmune & Arthritis

Early Rheumatoid Arthritis Treatment Shows Promise for Rapid Remission

Small study tests whether tocilizumab can achieve faster, deeper remission in newly diagnosed rheumatoid arthritis patients.

Clinical Trial
Mar 28, 2026 3
New Drug KPL-404 Shows Promise for Treatment-Resistant Rheumatoid Arthritis
Autoimmune & Arthritis

New Drug KPL-404 Shows Promise for Treatment-Resistant Rheumatoid Arthritis

Phase 2 trial tests novel therapy for patients who failed standard biologics and JAK inhibitors in 145-person study.

Clinical Trial
Mar 28, 2026 3
New Rheumatoid Arthritis Drug Shows Promise for Treatment-Resistant Patients
Autoimmune & Arthritis

New Rheumatoid Arthritis Drug Shows Promise for Treatment-Resistant Patients

Phase 3 trial tests otilimab against standard care in 550 patients who failed previous biologics and JAK inhibitors.

Clinical Trial
Mar 28, 2026 3
JAK Inhibitor Shows Promise for Persistent Pain in Rheumatoid Arthritis Patients
Autoimmune & Arthritis

JAK Inhibitor Shows Promise for Persistent Pain in Rheumatoid Arthritis Patients

Small study explores how tofacitinib may address chronic pain that persists even when inflammation is controlled in RA patients.

Clinical Trial
Mar 28, 2026 3
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