Degarelix vs Goserelin Head-to-Head in Advanced Prostate Cancer
Phase 3 trial pits next-gen GnRH antagonist degarelix against standard goserelin in prostate cancer hormone suppression.
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Phase 3 trial pits next-gen GnRH antagonist degarelix against standard goserelin in prostate cancer hormone suppression.
A completed phase 2 trial tested nab-paclitaxel combined with the checkpoint inhibitor pembrolizumab in patients with advanced urothelial cancer who cannot tolerate cisplatin.
A phase II trial tests whether 1Gy intestinal radiation can re-sensitize solid tumors that have stopped responding to immunotherapy.
A Phase 2 trial examines whether adding the anti-angiogenic drug bevacizumab to standard chemo improves outcomes in pediatric sarcoma.
A phase I trial tests SD-101, nivolumab, and radiation together against metastatic pancreatic cancer that has stopped responding to chemo.
A Phase 1/2 trial tests a custom cancer vaccine paired with checkpoint inhibitors in patients with advanced solid tumors.
A completed phase 3 trial compared A+AVD versus ABVD for advanced classical Hodgkin lymphoma, testing whether replacing bleomycin with brentuximab vedotin improves outcomes.
Phase 1 trial evaluates PF-06863135 (elranatamab) alone and with immunomodulatory agents to find safe dosing in heavily pretreated myeloma patients.
A phase II trial explored ipilimumab, nivolumab, and radiation therapy in advanced HPV-positive oropharyngeal cancer — but was terminated early.
A Phase 1/2 NCI trial tested PANVAC vaccinia and fowlpox vaccines plus immune booster sargramostim in advanced colorectal, breast, and ovarian cancers.
A completed trial examines how structured exercise reshapes body composition and sustains physical activity habits in breast cancer patients post-diagnosis.
MD Anderson's Phase 1/2 trial explored injecting rituximab directly into spinal fluid to target CNS lymphoid malignancies.