Cancer

51 articles in this topic

Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors
Cancer Research

Triple Immune Checkpoint Blockade Tested in Advanced Solid Tumors

A Phase 1/2 trial explores combining KIR, PD-1, and CTLA-4 inhibitors to unlock stronger anti-tumor immunity.

Clinical Trial
May 20, 2026 0
NCI Study Tests MRI and PET Scanning for Early Breast Cancer Detection in BRCA Carriers
Cancer Research

NCI Study Tests MRI and PET Scanning for Early Breast Cancer Detection in BRCA Carriers

A completed NCI trial evaluated advanced imaging and breast duct lavage in women with BRCA1/BRCA2 mutations to improve early cancer detection.

Clinical Trial
May 20, 2026 0
Phase I Trial Tests Ipilimumab Added to Chemoradiation for Advanced Cervical Cancer
Cancer Research

Phase I Trial Tests Ipilimumab Added to Chemoradiation for Advanced Cervical Cancer

NCI-sponsored trial evaluates safety and optimal dosing of immune checkpoint blockade following standard chemoradiation in locally advanced cervical cancer.

Clinical Trial
May 17, 2026 0
Dual Checkpoint Blockade Plus FOLFOX Chemo Tested in Metastatic Colorectal Cancer
Cancer Research

Dual Checkpoint Blockade Plus FOLFOX Chemo Tested in Metastatic Colorectal Cancer

A Phase 1/2 trial tests whether combining durvalumab, tremelimumab, and FOLFOX chemotherapy can safely boost immune response in mCRC.

Clinical Trial
May 17, 2026 0
Online Mindfulness Program Shows Promise for Gynecological Cancer Patients
Cancer Research

Online Mindfulness Program Shows Promise for Gynecological Cancer Patients

A Swiss feasibility trial tests digital mindfulness-based cancer recovery, tracking psychosocial outcomes, medication use, and biological markers.

Clinical Trial
May 16, 2026 0
Liquid Biopsy for Sarcoma: Can cfDNA and Telomere Mutations Predict Recurrence
Cancer Research

Liquid Biopsy for Sarcoma: Can cfDNA and Telomere Mutations Predict Recurrence

Researchers explored whether cancer-derived cell-free DNA and telomere maintenance mutations could serve as early warning biomarkers in soft tissue sarcoma patients.

Clinical Trial
May 16, 2026 0
Curcumin Added to Standard Chemo Tested in Metastatic Colorectal Cancer Trial
Cancer Research

Curcumin Added to Standard Chemo Tested in Metastatic Colorectal Cancer Trial

A Phase 2 trial explores whether oral curcumin can enhance Avastin/FOLFIRI chemotherapy outcomes in patients with unresectable colorectal metastases.

Clinical Trial
May 16, 2026 0
Triple Immunotherapy Combo for Recurrent SCLC Terminated After Enrolling 9 Patients
Cancer Research

Triple Immunotherapy Combo for Recurrent SCLC Terminated After Enrolling 9 Patients

A phase I/II trial combining nivolumab, ipilimumab, and lurbinectedin for relapsed SCLC was terminated early, raising questions about feasibility.

Clinical Trial
May 16, 2026 0
Apalutamide Plus Immunotherapy Combo Trial for Rare Prostate Cancer Variant Terminated
Cancer Research

Apalutamide Plus Immunotherapy Combo Trial for Rare Prostate Cancer Variant Terminated

A Phase 2 trial testing AR blockade combined with PD-1 inhibition in treatment-emergent neuroendocrine prostate cancer was terminated early.

Clinical Trial
May 15, 2026 0
PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early
Cancer Research

PULSAR Radiation Plus IMSA101 Immunotherapy Trial in Oligoprogressive Cancers Terminated Early

A Phase 2 trial combining adaptive stereotactic radiotherapy with IMSA101 and checkpoint inhibitors was halted after enrolling only 16 patients.

Clinical Trial
May 14, 2026 0
Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors
Cancer Research

Pfizer Terminates Phase 1 Trial of Novel Anti-PD-1/IL-15 Fusion Protein in Solid Tumors

Pfizer's first-in-human trial of PF-07209960, a dual-action immunotherapy fusion protein, was terminated after enrolling 37 patients.

Clinical Trial
May 14, 2026 0
Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer
Cancer Research

Amgen's PSMA Bispecific T-Cell Engager Acapatamab Tested in Advanced Prostate Cancer

Phase 1 trial of acapatamab, a PSMA-targeting bispecific T-cell engager, enrolls 212 men with metastatic castration-resistant prostate cancer.

Clinical Trial
May 13, 2026 0
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