Gut Microbiome Diversity Fails as Alzheimer's Biomarker in Major Meta-Analysis
A 23-study meta-analysis finds alpha-diversity cannot distinguish Alzheimer's or MCI from normal aging, but community structure shifts show more promise.
14 articles in this topic
A 23-study meta-analysis finds alpha-diversity cannot distinguish Alzheimer's or MCI from normal aging, but community structure shifts show more promise.
A major Cell Metabolism review reveals how microbiome metabolites reprogram immune cells to drive or prevent cardiometabolic disease.
Machine learning and whole-genome sequencing may finally give doctors the tools to predict bacterial resistance before treatment fails.
A new review identifies five critical methodological pitfalls undermining microbiome-aging studies and offers a practical checklist to fix them.
A comprehensive review reveals how gut microbial shifts drive inflammaging, metabolic decline, and organ dysfunction — and how to intervene.
A new review links adult cholestasis to pediatric genetic syndromes, opening doors to targeted therapies including novel bile acid transport inhibitors.
The British Society of Gastroenterology's expert panel takes stock of 10 years of microbiome advances and where the field is headed.
A new review maps the structural and functional changes that help the bowel compensate after resection, and highlights where knowledge gaps remain.
A landmark review reveals how diet, gut bacteria, and their metabolites determine the success of immune checkpoint blockade cancer therapy.
Aging disrupts gut microbiota and mTOR signaling, crippling vaccine responses — but targeted interventions may reverse this.
Age-related shifts in intestinal T cell populations may silently erode gut barrier function, accelerating the chronic inflammation that drives aging diseases.
A new review maps the bidirectional crosstalk between gut microbiota and cellular senescence driving multi-organ degeneration.