Reversing Aging

41 articles in this topic

NLRP3 Inflammasome Links Gum Disease Severity to Inflammaging
Longevity & Aging

NLRP3 Inflammasome Links Gum Disease Severity to Inflammaging

A completed trial examines how a key inflammation pathway connects periodontitis stages to the chronic low-grade inflammation of aging.

Clinical Trial
Jun 24, 2026 0
Pfizer-BioNTech Pivotal Trial Confirms BNT162b2 Safety and Efficacy Across Ages
Longevity & Aging

Pfizer-BioNTech Pivotal Trial Confirms BNT162b2 Safety and Efficacy Across Ages

The landmark Phase 1/2/3 trial that brought mRNA COVID-19 vaccination to the world, now completed with booster and variant data.

Clinical Trial
May 29, 2026 0
Edifice Health Trial Tests Supplement Formulas to Lower Inflammatory Age Score
Longevity & Aging

Edifice Health Trial Tests Supplement Formulas to Lower Inflammatory Age Score

A terminated RCT explored whether immunotype-targeted supplements could reduce iAge®, an AI-derived biomarker of chronic inflammation and immune aging.

Clinical Trial
May 25, 2026 0
GSK Tests Quadrivalent Flu Vaccine Safety and Lot Consistency in Adults
Longevity & Aging

GSK Tests Quadrivalent Flu Vaccine Safety and Lot Consistency in Adults

A Phase 3 trial evaluates a next-generation quadrivalent influenza vaccine against existing options, testing both immune response and manufacturing consistency.

Clinical Trial
May 22, 2026 0
Why Older Adults Get Less Protection From Flu and Shingles Vaccines
Longevity & Aging

Why Older Adults Get Less Protection From Flu and Shingles Vaccines

A completed Phase 2 trial investigates the immune mechanisms behind age-related vaccine failure in older adults.

Clinical Trial
May 18, 2026 0
Fisetin Tested as Senolytic Treatment to Reduce COVID-19 Complications
Longevity & Aging

Fisetin Tested as Senolytic Treatment to Reduce COVID-19 Complications

A Phase 2 pilot trial investigates whether the natural senolytic compound fisetin can reduce dysfunction and complications in COVID-19 patients.

Clinical Trial
May 8, 2026 0
Copenhagen Trial Pits Exercise, Fasting, and NR Against Each Other to Slow Aging
Longevity & Aging

Copenhagen Trial Pits Exercise, Fasting, and NR Against Each Other to Slow Aging

A completed RCT from the University of Copenhagen tests whether aerobic exercise, time-restricted feeding, or NR supplementation best improves biological aging markers in healthy older adults.

Clinical Trial
May 7, 2026 0
Stanford Study Shows Cyclic Sighing Breathing Reduces Stress Better Than Meditation
Longevity & Aging

Stanford Study Shows Cyclic Sighing Breathing Reduces Stress Better Than Meditation

28-day trial of 108 participants found specific breathing techniques outperformed mindfulness meditation for stress reduction and wellbeing.

Clinical Trial
Mar 29, 2026 12
Cellular Aging Markers May Predict Kidney Injury Risk After Heart Surgery
Longevity & Aging

Cellular Aging Markers May Predict Kidney Injury Risk After Heart Surgery

Study explores whether telomere biology and senescence biomarkers can forecast acute kidney injury following cardiac procedures.

Clinical Trial
Mar 29, 2026 0
Mindfulness Training Reduces Inflammation and Stress in Older Adults
Longevity & Aging

Mindfulness Training Reduces Inflammation and Stress in Older Adults

8-week stress management program shows promise for reducing inflammation and improving well-being in aging adults through mindfulness techniques.

Clinical Trial
Mar 29, 2026 0
Three Common Drugs Show Promise as Topical Anti-Aging Treatment in Small Trial
Longevity & Aging

Three Common Drugs Show Promise as Topical Anti-Aging Treatment in Small Trial

Researchers tested sirolimus, metformin, and diclofenac as topical skin treatments to target aging pathways in healthy volunteers.

Clinical Trial
Mar 29, 2026 1
Diabetes Drug Acarbose Shows Promise as Anti-Aging Therapy in Elderly Adults
Longevity & Aging

Diabetes Drug Acarbose Shows Promise as Anti-Aging Therapy in Elderly Adults

Small pilot study tests whether acarbose, a diabetes medication, can slow aging processes in healthy older adults through microbiome changes.

Clinical Trial
Mar 29, 2026 1
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