Natural Compounds May Fine-Tune a Key Aging Enzyme Better Than Drugs
A new review reveals how natural compounds could modulate EZH2 — a critical epigenetic enzyme — to slow aging without the risks of strong drug inhibition.
14 articles in this topic
A new review reveals how natural compounds could modulate EZH2 — a critical epigenetic enzyme — to slow aging without the risks of strong drug inhibition.
A new review argues that systemic blood recalibration and partial cellular reprogramming target different axes of aging and should be combined.
A systematic review of 27 human trials finds calorie restriction best modulates senescence markers, but direct evidence remains elusive.
Researchers propose five criteria to identify the best immune aging biomarkers, with inflammaging scores and functional assays emerging as top candidates.
A new review identifies PRMT enzymes as master regulators linking mitochondrial stress to sarcopenia and neuromuscular decline.
A sweeping review organizes 20 years of anti-aging pharmacology into three intervention axes and ranks the top compounds by research impact.
A new Cell Metabolism review from NIH identifies how ECM stiffening, poor blood flow, and mitochondrial failure lock tissues into accelerating decline.
A 2026 Cochrane update finds most evidence on turning frequency and position for pressure injury prevention remains very low certainty.
A scoping review exposes deep conceptual gaps in how physical resilience is defined and measured across aging and rehabilitation science.
A landmark review maps the structural, genetic, and molecular changes that erode lung function with age — and why reversing them matters.
New research reveals how people over 100 maintain youthful immune systems despite chronic inflammation, offering insights for healthy aging.
A new framework proposes organ-specific biological clocks using multi-omics data to better predict disease onset and aging trajectories.