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Brain Cooling Therapy Protects Aged Brains from Stroke Damage and Boosts Recovery
Researchers tested brain-targeted mild hypothermia in aged mice with permanent stroke, finding it significantly reduced blood-brain barrier damage, inflammation, and white matter loss while promoting long-term recovery. The treatment preserved brain blood vessels, reduced inflammatory cell infiltration, and enhanced regeneration of new blood vessels and brain cells. Cognitive and motor function improvements lasted at least 35 days, suggesting this approach could benefit elderly stroke patients who have limited treatment options.
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