Brain HealthBrain Protein Menin Controls Aging Speed and D-Serine Supplement Boosts Memory in Mice
Scientists have identified a brain protein called Menin as a potential hidden driver of aging. When Menin levels dropped in the hypothalamus of mice, the animals developed inflammation, memory problems, bone loss, and shorter lifespans. Researchers at Xiamen University found they could reverse several of these aging signs by restoring Menin directly in the brain. They also discovered that falling Menin levels caused a drop in D-serine, an amino acid neurotransmitter critical for memory and learning. Supplementing with D-serine improved cognitive function in aged mice. The findings position the hypothalamus as a central aging regulator and suggest both Menin and D-serine as promising targets for future anti-aging interventions in humans.
