Researchers at the Rejuvenation Science Institute in Brazil are working to reproduce controversial experiments suggesting that injecting fractions of pig plasma can reverse signs of aging in rats. This video features an interview with the scientists behind the replication effort, covering how the plasma fractions are prepared, early safety data from acute toxicity tests, and whether the rats tolerated the injections. The team also outlines their plans to scale up experiments and pursue open science collaboration. The original pig plasma findings generated significant excitement — and skepticism — in the longevity field. This replication attempt is a critical step toward validating or refuting those claims, with implications for whether blood-based therapies could one day slow or reverse aging in humans.