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CPAP Devices Miss 85% of Residual Sleep Apnea Nights Despite Normal ReadingsSleep & Recovery

CPAP Devices Miss 85% of Residual Sleep Apnea Nights Despite Normal Readings

Sleep apnea patients on CPAP therapy are often told their treatment is working based on device-reported AHI scores under 5 events per hour. But a large retrospective study comparing standard CPAP flow-based monitoring to cardiopulmonary coupling (CPC) sleep testing found a stark disconnect. Among nearly 25,000 matched nights from 465 patients, CPAP devices reported an average AHI of just 2.4 events per hour, while CPC testing found an average of 12.1. On nights CPAP flagged as successful, 85% still showed clinically significant residual apnea by CPC, and over a quarter had dangerously low oxygen levels for at least five minutes. This suggests widespread undertreatment is being missed in routine clinical care, with real implications for cardiovascular and cognitive healthspan.

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