SupplementsDr. Andrea Maier Separates Longevity Supplement Hype from Hard Evidence
Dr. Andrea Maier, director of the NUS Academy for Healthy Longevity, joins the Longevity by Design podcast to cut through supplement noise with data. Her lab audits found many NMN and urolithin A products fail to match label claims. A systematic review of over 5 million people showed multivitamins may help memory and blood pressure in older or at-risk adults, but offer little benefit to healthy individuals. She evaluates alpha-ketoglutarate, spermidine, curcumin, and melatonin by mechanism and trial quality. Her core message: measure biomarkers first, match supplements to identified deficiencies, and track outcomes using grip strength, walking speed, and wearable sleep data over time rather than relying on one-time assessments.
