Longevity & AgingHigh Cardiorespiratory Fitness Cuts Multimorbidity Risk by 21% Over 15 Years
A 15-year prospective study of 38,348 UK Biobank adults found that high cardiorespiratory fitness (CRF) reduces multimorbidity risk by 21% compared to low CRF. Using a validated submaximal cycling test, researchers grouped participants into low, moderate, and high CRF tertiles. High-CRF individuals took 1.27 years longer to develop multimorbidity and accumulated chronic diseases at a significantly slower annual rate. These findings held across age groups and multiple sensitivity analyses, suggesting that CRF is a powerful modifiable factor for compressing morbidity and extending healthy longevity.
