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Longevity Diet Low in Methionine Cuts Fat and Frailty in Aging MiceNutrition & Diet

Longevity Diet Low in Methionine Cuts Fat and Frailty in Aging Mice

Researchers at USC found that a modified Mediterranean-style diet low in protein and carefully adjusted in the amino acid methionine helped aging mice live healthier lives. Mice on this diet carried less body fat, showed fewer signs of frailty, and had better metabolic markers than mice on standard, Western, or ketogenic diets. Importantly, these benefits appeared despite the mice eating more food. An analysis of dietary data from over 200,000 people found that those eating more plant-based diets had lower rates of obesity and Type 2 diabetes. The findings suggest that the type of protein you eat — and its amino acid composition — may matter more than total protein quantity for long-term metabolic health.

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