Longevity Today
Academic PapersReviewsVideosPodcastsPress ReleasesClinical TrialsDrug ApprovalsTutorialsAnimations
All Articles
Sign In
Deep Dive Audio
New Meta-Analysis Settles the Debate on Negatives vs Positives for Muscle GrowthExercise & Fitness

New Meta-Analysis Settles the Debate on Negatives vs Positives for Muscle Growth

A major new meta-analysis of 26 studies and over 600 subjects examined whether the negative (lowering) or positive (lifting) phase of an exercise drives more muscle growth. Results showed that for upper body muscles, emphasizing the negative phase produced a small but statistically significant advantage in hypertrophy. For lower body muscles, both phases produced similar growth. Overall, across the whole body, the two phases were roughly equivalent. The practical takeaway is to control your negatives — especially for upper body work — but the popular belief that negatives are dramatically superior to positives for muscle growth is not strongly supported by the current evidence. Both phases contribute meaningfully to gains.

0:00--:--
Read Full Article
Longevity Today

Developed by the Clinical and Foundational Medicine Institute

AI-powered summaries of the world's best longevity research — from peer-reviewed journals to expert podcasts and YouTube deep-dives. Built for those who take their healthspan seriously.

info@LongevityToday.com

Categories

CancerHeart DiseaseAlzheimer'sParkinson'sDiabetesGut HealthNutritionStrength & FitnessSupplements & PeptidesStem CellsReversing AgingAuto-ImmunityAdvanced Therapies

Platform

  • All Articles
  • Membership Plans
  • Search
  • Newsletter

Newsletter

Weekly longevity research, summarized.

Enter your email to subscribe:

© 2026 Longevity Today. All rights reserved.

About UsPrivacy PolicyTerms of UseMedical Disclaimer

Content on Longevity Today is for informational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before making health decisions.