A groundbreaking study from the Weizmann Institute has overturned decades of scientific thinking about what determines how long we live. By analyzing massive twin databases, including twins raised apart, researchers discovered that genetics may control about half of lifespan variation—double previous estimates of 20-25%. Earlier studies underestimated genetic influence because they couldn't separate deaths from aging versus external factors like accidents and infections. Using new mathematical models and virtual twin simulations, the team filtered out these external deaths to reveal a much stronger genetic signal. This finding aligns with other complex traits and suggests specific longevity genes may be more discoverable than thought, potentially opening new therapeutic pathways for extending healthy lifespan.
