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Oxford Calculator Shows 98% of Statin Candidates Face Low Muscle RiskCancer Research

Oxford Calculator Shows 98% of Statin Candidates Face Low Muscle Risk

Researchers at the University of Oxford have built a personalized calculator that estimates an individual's risk of serious muscle disorders from statin medications. Drawing on anonymized health records from over 5.6 million people in England, the tool analyzes 22 health factors — including age, sex, BMI, and existing conditions — to predict risk over 1, 5, and 10 years. The study found that more than 98% of statin-eligible patients face low predicted risk of serious muscle complications. Despite this, over 60% of eligible patients are not taking statins, potentially missing significant protection against heart attacks and strokes. The calculator aims to replace vague fears with personalized data, helping doctors and patients make better-informed treatment decisions together.

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