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Parkinson's Patients Regain Movement After Brain Repair Using Their Own CellsLongevity & Aging

Parkinson's Patients Regain Movement After Brain Repair Using Their Own Cells

A San Diego biotech called Aspen Neuroscience has published early clinical results showing that Parkinson's patients may be able to regain lost brain function using their own cells. The therapy, called sasineprocel, takes a skin biopsy from the patient, reprograms those cells into a stem-cell-like state, then converts them into dopamine-producing neurons — the exact cells destroyed by Parkinson's. These lab-grown neurons are surgically implanted into the brain's movement-control region. In a Phase 1/2a trial of eight patients followed for 12 months, participants gained roughly two extra hours per day of steady, controlled movement. Motor scores improved, quality-of-life measures rose, and brain imaging confirmed the transplanted cells were surviving and integrating. No severe immune reactions occurred, and some patients reduced their medication dependence.

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