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siRNA Therapy Resets Aging Gene Networks in Diabetic Mice in Longevity BreakthroughLongevity & Aging

siRNA Therapy Resets Aging Gene Networks in Diabetic Mice in Longevity Breakthrough

A biotech startup called Junevity has shown that a type of RNA-based therapy can reset damaged gene networks back to a healthier state in diabetic mice. The therapy uses a molecule called siRNA, delivered to the liver, to silence a faulty gene regulator. The company reports lasting effects and no safety concerns in high-dose animal studies. Their platform combines large-scale biological data with AI to find targets for heart, metabolic, and brain diseases. A partnership with Eli Lilly is funding research into Parkinson's disease applications. While still in preclinical stages, this approach could eventually help reverse age-related gene dysfunction in humans.

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