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Smart Microneedle Patches Reverse Cell Aging to Heal Diabetic Wounds
Researchers developed innovative microneedle patches that deliver engineered stem cell vesicles to reverse cellular aging in diabetic wounds. The patches contain vesicles from fat-derived stem cells modified to overexpress Thymosin β4, a protein that combats cellular senescence. When applied to diabetic wounds in mice, these patches significantly reduced aging markers, promoted blood vessel formation, and accelerated healing compared to standard treatments.
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