Longevity & Aging

Smart Nanoparticles Protect Liver from Surgical Damage Using Targeted Antioxidant Delivery

Researchers developed smart nanoparticles that protect the liver from damage during surgery. The particles contain coenzyme Q10 and only release it when harmful oxygen molecules appear. In mouse studies, these nanoparticles significantly reduced liver injury by neutralizing damaging free radicals and preventing ferroptosis, a type of cell death involving iron and fat damage. The 100-nanometer particles showed promise as a targeted treatment for ischemia-reperfusion injury, which occurs when blood flow returns to oxygen-starved organs during surgical procedures.