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Proteostasis at the Edge: Advanced Mechanisms of the Ubiquitin-Proteasome SystemLongevity & Aging

Proteostasis at the Edge: Advanced Mechanisms of the Ubiquitin-Proteasome System

Explore the cutting-edge molecular architecture of the UPS — from E3 ligase conformational dynamics and proteasome regulatory networks to therapeutic exploitation via PROTACs, molecular glues, and deubiquitylase inhibitors.

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