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What GLP-1 Drugs Like Ozempic Actually Do to Your Brain, Heart and MetabolismGut & Microbiome

What GLP-1 Drugs Like Ozempic Actually Do to Your Brain, Heart and Metabolism

GLP-1 medications like Ozempic and Mounjaro are reshaping how medicine treats obesity — but they do far more than shrink waistlines. In this ZOE episode, Dr. Ania Jastreboff, a world-leading obesity researcher, explains how these drugs work on the brain to regulate hunger, why weight typically returns after stopping, and what side effects to expect. Beyond weight loss, GLP-1s show promise for reducing heart disease risk, improving blood sugar control, and addressing sleep apnoea. Dr. Jastreboff also tackles key questions around long-term use, muscle loss risks, the importance of adequate protein and exercise, and who these drugs are truly appropriate for. This is an essential primer for anyone considering or currently using GLP-1 therapy.

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