Autoimmune & Arthritis
B-Cell Depletion Cuts Chronic Graft-Versus-Host Disease Risk by 62%
A randomized trial shows prophylactic obinutuzumab dramatically reduces steroid-requiring cGVHD after bone marrow transplant.
Research Paper
May 3, 2026 0
Research Topic
Autoimmune & Arthritis
Autoimmune disorders, rheumatoid arthritis, systemic inflammation, and immune dysregulation
264 articles
Autoimmune & Arthritis
Premium
Reprogramming the Aged Immune System: Senolytics, Cytokine Blockade, and Epigenetic Rejuvenation
A mechanistic deep-dive into cutting-edge anti-inflammaging interventions — from senolytic pharmacology and precision cytokine targeting to partial reprogramming strategies that aim to restore youthful immune homeostasis.
TutorialAdvanced
May 2, 2026 0
Autoimmune & Arthritis
Premium
Immunosenescence: When Your Immune System Starts Misfiring
Go beyond inflammaging basics to understand how aging reshapes immune cell populations, triggers the SASP, and locks the body into a state of chronic low-grade inflammation at the molecular level.
TutorialIntermediate
May 2, 2026 0
Autoimmune & Arthritis
Structure-Guided Drug Design Unlocks Broader Antiviral Coverage Against Deadly Paramyxoviruses
Scientists reveal how a measles antiviral also blocks Nipah virus and use structural insights to engineer more potent next-generation inhibitors.
Research Paper
May 1, 2026 0
Autoimmune & Arthritis
NMN Treats Immune Thrombocytopenia by Restoring NAD+ in Macrophages
A phase 1/2 trial finds low-dose oral NMN safely raises platelet counts in steroid-refractory ITP via a novel immunometabolic mechanism.
Research Paper
Apr 30, 2026 0
Autoimmune & Arthritis
Your Childhood Flu Exposures Shape Antibody Responses Decades Later
Early influenza infections leave a lasting immunological imprint that determines how your immune system responds to entirely different flu strains later in life.
Research Paper
Apr 30, 2026 0
Autoimmune & Arthritis
Digital Twins Could Revolutionize How IBD Clinical Trials Are Run
Virtual patient replicas built from multimodal data may slash trial costs, generate synthetic control arms, and predict treatment response in IBD.
Review
Apr 30, 2026 0
Autoimmune & Arthritis
How Aging T Cells Drive Chronic Skin Inflammation and What Can Stop Them
Senescent T cells fuel psoriasis, eczema, and rosacea through toxic secretions. New therapies may finally break the cycle.
Review
Apr 29, 2026 0
Autoimmune & Arthritis
Thymosin Alpha-1 Activates Immune Cells to Shrink HIV Viral Reservoirs
A new in vitro study shows Thymosin α1 triggers dendritic cells to release IL-15, boosting CD8+ T cell killing and reducing HIV reservoir size.
Research Paper
Apr 28, 2026 0
Autoimmune & Arthritis
Cryoglobulinemia Triggers Rare Kidney Disease Pattern Captured in NEJM Case
A clinical case from Japan illustrates how cryoglobulinemia can drive membranoproliferative glomerulonephritis, a serious kidney complication.
Research Paper
Apr 28, 2026 0
Autoimmune & Arthritis
Thymosin Alpha-1 Cuts Sepsis Death Risk But Only in Specific Patient Subgroups
A 2025 meta-analysis of 11 RCTs finds Tα1 reduces 28-day sepsis mortality overall, but high-quality trial data tells a more nuanced story.
Research Paper
Apr 27, 2026 0
Autoimmune & Arthritis
New Immune Therapies Are Reshaping Treatment for Celiac Disease and Food Allergies
A major review maps emerging immunotherapies—from JAK inhibitors to microbiome interventions—that could transform care for celiac and food allergy patients.
Research Paper
Apr 27, 2026 0