Five-Drug HAART Cocktail Targets HIV Eradication in 40 Patients
A German proof-of-concept trial tests whether a maximal five-class antiretroviral regimen can deplete latent HIV reservoirs.
Autoimmune disorders, rheumatoid arthritis, systemic inflammation, and immune dysregulation
330 articles
A German proof-of-concept trial tests whether a maximal five-class antiretroviral regimen can deplete latent HIV reservoirs.
RA patients with interstitial lung disease show accelerated cellular aging markers — shorter telomeres and fewer mitochondrial DNA copies than RA patients without lung involvement.
A Phase 3 trial compares neutralizing antibody responses from inactivated-virus vaccine VLA2001 vs. AZD1222, plus a dedicated adolescent arm.
A Phase 4 trial tests whether simplifying HIV treatment to two drugs worsens hidden viral replication and immune dysfunction.
A completed Phase 3 trial evaluated whether the anti-TNF biologic infliximab safely and effectively treats plaque psoriasis.
A Phase 1/2 trial evaluates a dual RSV/hMPV vaccine candidate in older adults, targeting two major respiratory threats with a single shot.
Researchers repurpose mRNA-lipid nanoparticle technology to prevent and treat allergic asthma in mice, achieving ~100-fold reduction in airway eosinophils.
A major review outlines how targeted hematologic therapies are transforming outcomes in MGRS, a rare but serious cause of kidney injury.
A landmark Phase I trial of 108 adults tested the first adenovirus-vectored COVID-19 vaccine for safety and immune response.
A completed RCT tests whether 1-hour pathogen detection paired with antimicrobial stewardship slashes broad-spectrum antibiotic days in HAP patients.
A new WHO public health emergency declaration over Bundibugyo Ebola raises urgent questions about health equity and international pandemic preparedness.
Scientists used CRISPR to find SPART, a human gene that restricts a whole family of dangerous flaviviruses including Zika and dengue.