Research Topic

Cancer Research

Oncology, cancer prevention, tumor biology, and immunotherapy relevant to longevity

316 articles

Chemotherapy Plus Hormones vs Hormones Alone for Older Women with High-Risk Breast Cancer
Cancer Research

Chemotherapy Plus Hormones vs Hormones Alone for Older Women with High-Risk Breast Cancer

ASTER 70s trial compares treatment intensities for women 70+ with genomically high-risk breast cancer to optimize outcomes while minimizing toxicity.

Research Paper
Apr 4, 2026 0
PROTAC Nanomedicine Destroys Cancer Protein to Trigger Cell Death via Ferroptosis
Cancer Research

PROTAC Nanomedicine Destroys Cancer Protein to Trigger Cell Death via Ferroptosis

Novel nanoparticle combines protein degrader with light therapy to reprogram cancer metabolism and eliminate breast tumors.

Research Paper
Apr 4, 2026 0
Single Cell Analysis Reveals New Thyroid Cancer Immunotherapy Targets
Cancer Research

Single Cell Analysis Reveals New Thyroid Cancer Immunotherapy Targets

Researchers use advanced cell profiling to develop personalized immune treatments for thyroid cancer patients.

Research Paper
Apr 4, 2026 0
Taurine From Bone Marrow Fuels Aggressive Leukemia Growth
Cancer Research

Taurine From Bone Marrow Fuels Aggressive Leukemia Growth

New research reveals how bone marrow cells produce taurine that feeds leukemia stem cells, offering potential therapeutic targets.

Research Paper
Apr 4, 2026 0
Cancer Protein IGF2BP3 Drives Metastasis Through Novel Autophagy Mechanism
Cancer Research

Cancer Protein IGF2BP3 Drives Metastasis Through Novel Autophagy Mechanism

New research reveals how IGF2BP3 protein promotes triple-negative breast cancer spread by hijacking cellular recycling processes.

Research Paper
Apr 4, 2026 0
Targeted Therapy Shows Promise for Aggressive Brain Cancer in Precision Medicine Trial
Cancer Research

Targeted Therapy Shows Promise for Aggressive Brain Cancer in Precision Medicine Trial

Phase 1/2 umbrella trial matches glioblastoma patients to targeted treatments based on tumor genetics, with temsirolimus showing significant benefit.

Research Paper
Apr 4, 2026 0
Green Tea Nanoparticles Boost Mitochondria to Fight Cancer and Enhance Immunotherapy
Cancer Research

Green Tea Nanoparticles Boost Mitochondria to Fight Cancer and Enhance Immunotherapy

Engineered green tea compound nanoparticles activate cellular powerhouses to suppress tumor growth and improve immune response against melanoma.

Research Paper
Apr 4, 2026 0
New Dual MEK/mTOR Inhibitor Shows Promise Against Cancer Drug Resistance
Cancer Research

New Dual MEK/mTOR Inhibitor Shows Promise Against Cancer Drug Resistance

Scientists develop LP-65, a single molecule targeting two cancer pathways simultaneously, showing enhanced anti-tumor effects in lab studies.

Research Paper
Apr 4, 2026 0
RNA Polymerase Inhibitor CX-5461 Triggers Cancer Cell Death via Iron Overload
Cancer Research

RNA Polymerase Inhibitor CX-5461 Triggers Cancer Cell Death via Iron Overload

New study reveals how blocking ribosome production makes cancer cells vulnerable to ferroptosis, an iron-dependent cell death pathway.

Research Paper
Apr 4, 2026 0
Cancer Protein OASL Hijacks Cell Machinery to Fuel Tumor Growth Through Fat Production
Cancer Research

Cancer Protein OASL Hijacks Cell Machinery to Fuel Tumor Growth Through Fat Production

New research reveals how a cancer-promoting protein reprograms cellular fat production to accelerate tumor progression.

Research Paper
Apr 4, 2026 0
Histone Enzyme ASH1L Drives Cancer Spread to Bones Through Immune Cell Hijacking
Cancer Research

Histone Enzyme ASH1L Drives Cancer Spread to Bones Through Immune Cell Hijacking

New study reveals how cancer cells reprogram bone immune cells to fuel metastasis, offering potential therapeutic targets.

Research Paper
Apr 4, 2026 0
Multi-omics study identifies two genes that drive glioblastoma brain cancer risk
Cancer Research

Multi-omics study identifies two genes that drive glioblastoma brain cancer risk

Researchers used advanced genetic analysis to find LGALS9 and SELL genes causally linked to aggressive brain tumors, revealing new treatment targets.

Research Paper
Apr 4, 2026 0
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