Research Topic

Longevity & Aging

Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization

1311 articles

NIA Symposium Reveals Critical Gaps in Aging Biomarker Development
Longevity & Aging

NIA Symposium Reveals Critical Gaps in Aging Biomarker Development

Leading researchers identify key challenges in validating aging biomarkers for clinical use, emphasizing need for longitudinal studies.

Research Paper
Apr 2, 2026 0
Epigenetic Changes Drive Biological Aging at the Molecular Level
Longevity & Aging

Epigenetic Changes Drive Biological Aging at the Molecular Level

New research explores how epigenetic modifications control the aging process and potential therapeutic targets.

Research Paper
Apr 2, 2026 0
CXCR4 Blocker Shows Promise for Early COPD Treatment in Preclinical Study
Longevity & Aging

CXCR4 Blocker Shows Promise for Early COPD Treatment in Preclinical Study

Targeting CXCR4 protein improved lung function and reduced heart damage in early COPD mouse models, suggesting new therapeutic approach.

Research Paper
Apr 2, 2026 0
Mitochondrial NAD+ Levels Control Liver Regeneration Speed
Longevity & Aging

Mitochondrial NAD+ Levels Control Liver Regeneration Speed

New study reveals mitochondrial NAD+ concentration, not total cellular levels, determines how fast the liver can regenerate after injury.

Research Paper
Apr 2, 2026 0
NAD+ Boosters Show Promise in Clinical Trials for Aging and Neurodegeneration
Longevity & Aging

NAD+ Boosters Show Promise in Clinical Trials for Aging and Neurodegeneration

Comprehensive review reveals emerging clinical evidence for NAD+ precursors in treating age-related diseases and cognitive decline.

Research Paper
Apr 2, 2026 0
Accelerated Biological Aging Linked to Faster Glaucoma Progression in New Study
Longevity & Aging

Accelerated Biological Aging Linked to Faster Glaucoma Progression in New Study

DNA methylation patterns reveal that patients with faster biological aging experience more rapid vision loss from glaucoma.

Research Paper
Apr 2, 2026 0
GrimAge Clock Best Predicts Physical Function Decline Across All Adult Ages
Longevity & Aging

GrimAge Clock Best Predicts Physical Function Decline Across All Adult Ages

Study of 1,014 adults finds GrimAge epigenetic clock most accurately links biological aging to physical performance from age 20-104.

Research Paper
Apr 2, 2026 0
GrimAge Epigenetic Clocks Accurately Predict Death Risk in Large Study
Longevity & Aging

GrimAge Epigenetic Clocks Accurately Predict Death Risk in Large Study

Analysis of 1,942 people shows GrimAge and GrimAge2 epigenetic clocks outperform other aging biomarkers at predicting mortality.

Research Paper
Apr 2, 2026 0
Dr. Charles Brenner Reveals NAD+ Secrets for Longevity and Cellular Health
Longevity & Aging

Dr. Charles Brenner Reveals NAD+ Secrets for Longevity and Cellular Health

Leading NAD+ researcher Dr. Charles Brenner shares breakthrough insights on cellular energy, aging, and practical longevity strategies.

Video
Apr 2, 2026 0
Peter Attia's Real-World Longevity Toolkit: DEXA Scans, Protein, and Habit Formation
Longevity & Aging

Peter Attia's Real-World Longevity Toolkit: DEXA Scans, Protein, and Habit Formation

Practical longevity strategies across decades of life, from DEXA interpretation to mTOR concerns with high protein intake.

Podcast
Apr 2, 2026 0
Warning Signs Your Body Is Sending You According to Dr Darshan Shah
Longevity & Aging

Warning Signs Your Body Is Sending You According to Dr Darshan Shah

Max Lugavere interviews Dr. Darshan Shah about critical health warning signs you shouldn't ignore.

Video
Apr 2, 2026 0
CRISPR Screen Reveals lncRNAs That Control Cellular Aging and DNA Repair
Longevity & Aging

CRISPR Screen Reveals lncRNAs That Control Cellular Aging and DNA Repair

Researchers used advanced genetic screens to identify long noncoding RNAs that regulate senescence, finding therapeutic targets for age-related diseases.

Research Paper
Apr 2, 2026 0
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