Revolutionary Mix-and-Match Method Creates Complex 3D Drug Molecules
New synthetic chemistry approach enables modular assembly of three-dimensional small molecules for drug discovery.
Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization
1427 articles
New synthetic chemistry approach enables modular assembly of three-dimensional small molecules for drug discovery.
New molecular AI system combines atomic-scale data to accelerate discovery of longevity-enhancing compounds and therapies.
Scientists propose space environments as unique models for studying accelerated aging mechanisms and potential interventions.

Bryan Johnson discusses a significant development in his anti-aging Blueprint protocol journey.
Analysis reveals gap in podcast coverage of cellular senescence despite growing research interest in this aging mechanism.
Updated practice guidelines aim to improve safety and consistency of sedation techniques used outside operating rooms.
Natural compounds like quercetin eliminate harmful senescent cells in the uterus, improving decidualization and reducing migration linked to endometriosis.
Removing senescent cells after flu infection accelerated lung repair and prevented chronic damage in mice.
New research reveals how the metabolite α-ketoglutarate enhances trophectoderm formation from human embryonic stem cells.
Comprehensive analysis of 204 countries shows intimate partner violence and child sexual abuse cause millions of disability-adjusted life years lost annually.
Three gas molecules (H2S, NO, CO) can both prevent inflammatory cell death and promote cancer cell destruction through different pathways.
New research reveals how SIRT3 protects bone-building cells from ferroptosis during glucocorticoid treatment, offering therapeutic targets.