Research Topic

Longevity & Aging

Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization

1427 articles

Combination SMA Therapy Shows Promise: Gene Therapy Plus Oral Drug Improves Outcomes
Longevity & Aging

Combination SMA Therapy Shows Promise: Gene Therapy Plus Oral Drug Improves Outcomes

Real-world study of 20 children shows adding risdiplam after gene therapy improved motor, breathing, and swallowing function in spinal muscular atrophy.

Research Paper
Mar 31, 2026 0
HPV Vaccine Shows Promise for Reducing Precancerous Skin Lesions
Longevity & Aging

HPV Vaccine Shows Promise for Reducing Precancerous Skin Lesions

Clinical trial finds standard HPV vaccination significantly reduces actinic keratosis burden in adults with multiple lesions.

Research Paper
Mar 31, 2026 0
RSV Vaccines Show Strong Protection for Older Adults and Infants in Major Review
Longevity & Aging

RSV Vaccines Show Strong Protection for Older Adults and Infants in Major Review

Comprehensive analysis of 14 trials reveals RSV vaccines reduce respiratory illness by up to 77% in older adults and 74% in infants through maternal vaccination.

Research Paper
Mar 31, 2026 0
AI Model Predicts Heart Disease Risk Better Than Traditional Methods Using Blood Biomarkers
Longevity & Aging

AI Model Predicts Heart Disease Risk Better Than Traditional Methods Using Blood Biomarkers

Machine learning approach combining plasma biomarkers with traditional risk factors improves cardiovascular disease prediction and risk stratification.

Research Paper
Mar 31, 2026 0
Senescent Immune Cell Proteins Predict Age-Related Health Decline in Humans
Longevity & Aging

Senescent Immune Cell Proteins Predict Age-Related Health Decline in Humans

Scientists identify blood biomarkers from aging immune cells that predict mobility, metabolism, and body composition changes in over 1,000 adults.

Research Paper
Mar 31, 2026 0
HPV Testing Could Eliminate Cervical Cancer 10 Years Earlier Than Current Methods
Longevity & Aging

HPV Testing Could Eliminate Cervical Cancer 10 Years Earlier Than Current Methods

Mathematical modeling shows high-risk HPV testing with increased vaccination rates could achieve cervical cancer elimination by 2034 in South Korea.

Research Paper
Mar 31, 2026 0
Caffeinated Coffee Linked to 18% Lower Dementia Risk in 43-Year Harvard Study
Longevity & Aging

Caffeinated Coffee Linked to 18% Lower Dementia Risk in 43-Year Harvard Study

Large-scale study of 131,821 people finds moderate caffeinated coffee consumption significantly reduces dementia risk and improves cognitive function.

Research Paper
Mar 31, 2026 0
Tirzepatide Shows Cardiovascular Safety in Major Diabetes Trial
Longevity & Aging

Tirzepatide Shows Cardiovascular Safety in Major Diabetes Trial

Large trial finds tirzepatide as safe as dulaglutide for heart outcomes in type 2 diabetes patients with existing cardiovascular disease.

Research Paper
Mar 31, 2026 0
Oral Bacteria Drive Brain Inflammation Through Oxidative Stress Pathways
Longevity & Aging

Oral Bacteria Drive Brain Inflammation Through Oxidative Stress Pathways

New research reveals how oral microbiome imbalances trigger neurodegeneration through redox signaling and inflammation.

Research Paper
Mar 31, 2026 0
Oral Microbiome Changes Linked to Mental Health Disorders Across Six Conditions
Longevity & Aging

Oral Microbiome Changes Linked to Mental Health Disorders Across Six Conditions

Meta-analysis reveals distinct oral bacteria patterns in autism, schizophrenia, depression and other mental disorders.

Research Paper
Mar 31, 2026 0
Farm Animal Exposure Alters Oral Microbiome in Agricultural Workers
Longevity & Aging

Farm Animal Exposure Alters Oral Microbiome in Agricultural Workers

Large study reveals how raising different farm animals changes the bacterial communities in farmers' mouths, with implications for disease risk.

Research Paper
Mar 31, 2026 0
Poor Oral Health Linked to Cognitive Decline Through Microbiome Changes
Longevity & Aging

Poor Oral Health Linked to Cognitive Decline Through Microbiome Changes

Large community study reveals how periodontal disease and oral bacteria may accelerate brain aging through inflammatory pathways.

Research Paper
Mar 31, 2026 0
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