Research Topic

Longevity & Aging

Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization

1460 articles

Oral Bacteria Drive Inflammatory Bowel Disease Through Gut-Mouth Connection
Longevity & Aging

Oral Bacteria Drive Inflammatory Bowel Disease Through Gut-Mouth Connection

New research reveals how oral microbiome dysbiosis triggers IBD inflammation through shared immune pathways and bacterial translocation.

Research Paper
Mar 31, 2026 0
Periodontal Therapy Reshapes Oral Microbiome in Immunodeficient Children
Longevity & Aging

Periodontal Therapy Reshapes Oral Microbiome in Immunodeficient Children

Study reveals how dental treatment transforms bacterial communities in children with compromised immune systems.

Research Paper
Mar 31, 2026 0
Oral Bacteria Drive Cancer Development Through Multiple Carcinogenic Pathways
Longevity & Aging

Oral Bacteria Drive Cancer Development Through Multiple Carcinogenic Pathways

New research reveals how specific oral microbes produce toxins, trigger inflammation, and promote cancer progression in the mouth.

Research Paper
Mar 31, 2026 0
Oral Microbiome Changes May Predict Healthy Aging and Longevity
Longevity & Aging

Oral Microbiome Changes May Predict Healthy Aging and Longevity

Comprehensive review reveals how oral bacteria shift with age and link to frailty, offering new targets for healthy aging interventions.

Research Paper
Mar 31, 2026 0
Oral Bacteria May Predict Lung Cancer Risk Through Genetic Analysis
Longevity & Aging

Oral Bacteria May Predict Lung Cancer Risk Through Genetic Analysis

Mendelian randomization study identifies specific oral microbes that causally increase or decrease lung cancer risk.

Research Paper
Mar 31, 2026 0
Oral Bacteria May Drive Alzheimer's Through Brain-Gut Connection
Longevity & Aging

Oral Bacteria May Drive Alzheimer's Through Brain-Gut Connection

New research reveals how oral microbiome imbalances trigger neuroinflammation and cognitive decline through systemic pathways.

Research Paper
Mar 31, 2026 0
New Framework Needed to Assess Safety of Microbiome-Targeting Products
Longevity & Aging

New Framework Needed to Assess Safety of Microbiome-Targeting Products

Academic-industry workshop identifies key challenges in evaluating long-term safety of products designed to modify human microbiomes.

Research Paper
Mar 31, 2026 0
Oral Bacteria May Directly Impact Mental Health Through Brain Pathways
Longevity & Aging

Oral Bacteria May Directly Impact Mental Health Through Brain Pathways

New review reveals how oral microbiome disruption could contribute to depression, anxiety, and neurodegenerative diseases via direct neural connections.

Research Paper
Mar 31, 2026 0
Higher Oral Microbiome Diversity Linked to Lower Kidney Stone Risk in Large US Study
Longevity & Aging

Higher Oral Microbiome Diversity Linked to Lower Kidney Stone Risk in Large US Study

Analysis of 5,870 adults reveals inverse relationship between oral bacterial diversity and kidney stone formation, suggesting new prevention targets.

Research Paper
Mar 31, 2026 0
Diet Shapes Oral Microbiome and Systemic Inflammation Through Multiple Pathways
Longevity & Aging

Diet Shapes Oral Microbiome and Systemic Inflammation Through Multiple Pathways

Review reveals how plant-based diets, caloric restriction, and processed foods differently impact oral bacteria and whole-body health.

Research Paper
Mar 31, 2026 0
Oral Bacteria Linked to Death Risk in Major US Population Study
Longevity & Aging

Oral Bacteria Linked to Death Risk in Major US Population Study

First large-scale study reveals specific oral microbes associated with mortality risk in nearly 8,000 Americans.

Research Paper
Mar 31, 2026 0
Traditional Chinese Medicine Formula Treats Post-Stroke Depression via Gut Microbiome
Longevity & Aging

Traditional Chinese Medicine Formula Treats Post-Stroke Depression via Gut Microbiome

Xiaoyaosan herbal formula improves depression after stroke by restoring healthy gut bacteria and reducing brain inflammation in mice.

Research Paper
Mar 31, 2026 0
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