Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization
1460 articles
Study finds urolithin A from pomegranates reduces schizophrenia-like behaviors and cognitive deficits in female rats by targeting brain inflammation.
Study reveals cellular defects in eye disease that shares features with neurodegenerative conditions, pointing to potential treatments.
New research reveals how this pomegranate compound protects lungs during sepsis by restoring cellular powerhouses and reducing inflammation.
Study reveals how urolithin A activates cellular cleanup to reduce dangerous lung inflammation from radiation therapy.
Gut metabolite urolithin A enhances mitochondrial quality control through calcium signaling, extending lifespan in worms and protecting human cells.
Four-week trial shows mitophagy inducer urolithin A expands youthful T cells and improves immune metabolism in healthy adults aged 45-70.
Groundbreaking multicenter trial will test rapamycin's ability to extend healthy lifespan in companion dogs, offering insights for human aging.
Cycloastragenol from Astragalus plant enhances brain immune cell function and reduces amyloid plaques in Alzheimer's mouse models.
Plant-derived cycloastragenol reduced inflammation and improved survival in septic mice by blocking key immune pathways.
Scientists discover a circular RNA that reactivates telomerase enzyme, extending telomeres and reversing aging markers in cells and tissues.
New research reveals some cancer-associated POT1 mutations don't just break telomere protection—they actively promote excessive telomere growth.
Researchers developed MARLIN, an AI classifier that rapidly identifies leukemia subtypes from DNA methylation, potentially transforming cancer diagnosis.
