Research Topic

Longevity & Aging

Aging biology, lifespan extension, hallmarks of aging, and healthspan optimization

1509 articles

Uremic Toxins Drive Cognitive Decline in Kidney Disease Patients
Longevity & Aging

Uremic Toxins Drive Cognitive Decline in Kidney Disease Patients

Comprehensive review reveals how kidney disease toxins damage the brain and explores promising therapeutic interventions.

Research Paper
Mar 31, 2026 0
New Lipid Nanoparticles Deliver Anti-Aging CAR-T Therapy Without Antibodies
Longevity & Aging

New Lipid Nanoparticles Deliver Anti-Aging CAR-T Therapy Without Antibodies

Researchers develop cardiolipin-inspired nanoparticles that target senescent cells in vivo, offering a simpler approach to CAR-T therapy for aging.

Research Paper
Mar 31, 2026 0
AI Creates Multi-Organ Aging Clocks Using MRI Scans to Predict Disease Risk
Longevity & Aging

AI Creates Multi-Organ Aging Clocks Using MRI Scans to Predict Disease Risk

Researchers developed seven organ-specific aging clocks from MRI data that predict disease risk and mortality better than chronological age alone.

Research Paper
Mar 31, 2026 0
Brain Scans Predict Aging Speed and Disease Risk From Single MRI Image
Longevity & Aging

Brain Scans Predict Aging Speed and Disease Risk From Single MRI Image

New AI tool measures biological aging pace from brain scans, predicting dementia, frailty, and mortality better than chronological age.

Research Paper
Mar 31, 2026 0
New Pace of Aging Tool Predicts Healthspan Better Than Chronological Age
Longevity & Aging

New Pace of Aging Tool Predicts Healthspan Better Than Chronological Age

Researchers developed a biomarker-based method to measure aging speed that outperforms chronological age in predicting disease, disability, and death.

Research Paper
Mar 31, 2026 0
Oral Bacteria Changes Drive Major Diseases in Aging Adults
Longevity & Aging

Oral Bacteria Changes Drive Major Diseases in Aging Adults

Age-related shifts in mouth bacteria linked to Alzheimer's, diabetes, heart disease, and other conditions affecting older adults.

Research Paper
Mar 31, 2026 0
Sterilization Extends Lifespan Across Vertebrate Species, New Research Shows
Longevity & Aging

Sterilization Extends Lifespan Across Vertebrate Species, New Research Shows

Large-scale study reveals sterilization and contraception increase life expectancy in both males and females across vertebrate species.

Research Paper
Mar 31, 2026 0
Stem Cell Secretions Show Promise Against Parkinson's Disease in Rat Study
Longevity & Aging

Stem Cell Secretions Show Promise Against Parkinson's Disease in Rat Study

Neural-induced stem cell secretions protected dopamine neurons and reduced toxic protein buildup in Parkinson's disease model.

Research Paper
Mar 31, 2026 0
Sepsis Survivors' Muscle Weakness Linked to Broken Cellular Cleanup System
Longevity & Aging

Sepsis Survivors' Muscle Weakness Linked to Broken Cellular Cleanup System

New research reveals why sepsis survivors suffer lasting muscle weakness and identifies a potential treatment using urolithin A.

Research Paper
Mar 31, 2026 0
Gut Bacteria Shield Against Heart Inflammation in Kawasaki Disease Model
Longevity & Aging

Gut Bacteria Shield Against Heart Inflammation in Kawasaki Disease Model

Study reveals how specific gut microbes protect against cardiovascular inflammation, offering new therapeutic targets for vasculitis.

Research Paper
Mar 31, 2026 0
CAR-T Cell Therapy Shows Durable 3-Year Benefits in Lymphoma Treatment
Longevity & Aging

CAR-T Cell Therapy Shows Durable 3-Year Benefits in Lymphoma Treatment

Lisocabtagene maraleucel demonstrates superior long-term survival compared to standard chemotherapy in relapsed B-cell lymphoma patients.

Research Paper
Mar 31, 2026 0
AI-Powered Supplement Stacks Lead 2026 Longevity Breakthroughs
Longevity & Aging

AI-Powered Supplement Stacks Lead 2026 Longevity Breakthroughs

Dr. Jeffrey Gladden explores how AI is revolutionizing personalized longevity protocols and supplement stacks for optimal healthspan.

Podcast
Mar 30, 2026 1
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