Research Topic

Metabolic Health

Insulin resistance, blood sugar regulation, metabolic syndrome, and body composition

461 articles

NIH Spotlights Pancreatic Aging, Heart Risk and Testosterone in Cancer Defense
Metabolic Health

NIH Spotlights Pancreatic Aging, Heart Risk and Testosterone in Cancer Defense

Three new NIH-funded findings tackle metabolic aging, cardiovascular risk, and a surprising hormonal brake on brain tumors.

Press Release
May 14, 2026 0
GLP-1 Drugs and Metformin Trim BMI in Obese Youth but Long-Term Safety Remains Unknown
Metabolic Health

GLP-1 Drugs and Metformin Trim BMI in Obese Youth but Long-Term Safety Remains Unknown

A Cochrane review of 37 RCTs finds obesity drugs modestly reduce weight in adolescents, but evidence quality is low and long-term data are absent.

Review
May 14, 2026 0
Recurrent Low Blood Sugar Does Not Rewire Brain Glucose Transport in Type 1 Diabetes
Metabolic Health

Recurrent Low Blood Sugar Does Not Rewire Brain Glucose Transport in Type 1 Diabetes

A rigorous MRI-based study finds that repeated hypoglycemia episodes leave brain glucose transport kinetics unchanged, challenging a leading hypothesis.

Research Paper
May 14, 2026 0
Gut Device Outperforms Semaglutide for Weight Loss and Insulin Sensitivity in Animal Study
Metabolic Health

Gut Device Outperforms Semaglutide for Weight Loss and Insulin Sensitivity in Animal Study

A novel endoluminal device implanted in the gut improved insulin sensitivity and weight control beyond what semaglutide achieved in a pig model.

Research Paper
May 14, 2026 0
CGM Devices for Biohackers Ranked by Evidence in 2026
Metabolic Health

CGM Devices for Biohackers Ranked by Evidence in 2026

A head-to-head review of 10 CGM devices for healthy adults, weighing real-world accuracy data against limited longevity evidence.

Review
May 13, 2026 0
NIH Funds Pancreas Atlas and Heart Risk Models Targeting Age-Related Disease
Metabolic Health

NIH Funds Pancreas Atlas and Heart Risk Models Targeting Age-Related Disease

Three NIH-funded studies this week tackle metabolic decline, cardiac risk, and brain tumors — all with aging implications.

Press Release
May 13, 2026 0
Cochrane Review Protocol Sets Stage for Definitive Insulin Regimen Comparison in Type 1 Diabetes
Metabolic Health

Cochrane Review Protocol Sets Stage for Definitive Insulin Regimen Comparison in Type 1 Diabetes

A major Cochrane network meta-analysis protocol will rank all insulin regimens by efficacy and safety for adults with type 1 diabetes.

Research Paper
May 13, 2026 0
SGLT2 Inhibitors May Not Benefit Lean Non-Diabetic CKD Patients
Metabolic Health

SGLT2 Inhibitors May Not Benefit Lean Non-Diabetic CKD Patients

Landmark CKD trials enrolled mostly overweight patients — new evidence questions whether SGLT2 inhibitors work for lean, non-diabetic individuals.

Research Paper
May 12, 2026 0
SGLT2 Inhibitors May Shield Kidneys From Acute Injury Through Multiple Mechanisms
Metabolic Health

SGLT2 Inhibitors May Shield Kidneys From Acute Injury Through Multiple Mechanisms

A comprehensive review finds SGLT2 inhibitors reduce AKI risk in humans via hemodynamic, metabolic, and cellular protective pathways.

Research Paper
May 12, 2026 0
CGMs for Longevity Seekers: Real Benefits, Real Limits and What the Evidence Actually Shows
Metabolic Health

CGMs for Longevity Seekers: Real Benefits, Real Limits and What the Evidence Actually Shows

Expert reviews of top CGM platforms reveal genuine metabolic insights — but no proof they extend lifespan in healthy adults.

Review
May 12, 2026 0
Skin-Worn Microneedle Sensors Track Glucose and Metabolites Without Blood Draws
Metabolic Health

Skin-Worn Microneedle Sensors Track Glucose and Metabolites Without Blood Draws

Wearable microneedle patches tap interstitial fluid to monitor glucose, lactate, and electrolytes in real time — no needles, no lab.

Research Paper
May 11, 2026 0
AMPK at the Cutting Edge: Isoforms, Substrates, and Therapeutic Frontiers
Metabolic Health
Premium

AMPK at the Cutting Edge: Isoforms, Substrates, and Therapeutic Frontiers

Master the advanced molecular architecture of AMPK — from isoform-specific signaling and spatial compartmentalization to emerging pharmacological strategies targeting the energy sensor at the heart of longevity biology.

TutorialAdvanced
May 10, 2026 0
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