Stem cells, exosomes, gene therapy, peptides, hyperbaric oxygen, and epigenetic reprogramming
348 articles
A comprehensive review reveals how biomaterials, stem cells, and 3D bioprinting are converging to restore damaged endometrial tissue and treat infertility.
Intellia's in vivo CRISPR treatment edits genes directly inside living patients and just cleared a Phase 3 trial — a world first.
Intellia Therapeutics reports a landmark Phase 3 win for CRISPR gene editing, potentially offering a one-time cure for a debilitating genetic disease.
Single-cell sequencing reveals ferroptosis drives pulpitis; thymosin α1 restores GPX4, cuts iron overload, and reduces inflammation in cells and rats.
Engineered immune cells simultaneously dissolve cardiac fibrosis and rebuild heart muscle in mice, offering a dual-action therapy for heart failure.
Scientists discover muscle cells bypass normal nuclear pores to export oversized RNA transcripts via a newly identified budding pathway.
Three days of GDF11 infusion post-injury preserved pericytes, protected the blood-spinal cord barrier, and improved functional recovery in mice.
A new laser-based technique repairs vacuum-dehydrated proteins on cryoEM grids, achieving near-native resolution comparable to conventional plunge freezing.
PARP inhibitors have transformed cancer treatment, but resistance and toxicity are emerging as serious limits to their long-term effectiveness.
A miniaturized PEMF device failed to raise SpO2 in healthy rats, suggesting COVID-19 benefits may be disease-specific.
A CRISPR-based adenine base editor restores CFTR function in airway cells and intestinal organoids from CF patients with a previously undruggable mutation.
Regeneron's Otarmeni marks a historic milestone as the first FDA-approved gene therapy targeting a rare genetic form of hearing loss.
