Small Molecules Reprogram Human Cells Without Genetic Engineering
Chinese researchers decode how chemical cocktails alone can convert adult human cells into pluripotent stem cells, bypassing gene editing.
Stem cells, exosomes, gene therapy, peptides, hyperbaric oxygen, and epigenetic reprogramming
420 articles
Chinese researchers decode how chemical cocktails alone can convert adult human cells into pluripotent stem cells, bypassing gene editing.
A review of iPSC-based regenerative medicine charts the path from Parkinson's disease models to real-world cell replacement therapies.
A terminated multicenter RCT examined whether mechanical cough assistance plus NIV could cut re-intubation rates in ICU patients with weak cough.
Discover exosomes — the microscopic 'text messages' your cells send to coordinate healing, aging, and repair throughout your body.
Astellas reports encouraging early-stage results for a stem cell-derived treatment targeting age-related eye disease, though data remains limited.
A comprehensive review evaluates five energy harvesting technologies that convert body heat, motion, and glucose into power for implantable devices.
A comprehensive review maps how mesenchymal stem cells and their exosomes combat Alzheimer's, atherosclerosis, osteoporosis, and ovarian failure.
A novel photoactivatable drug system uses NK immune cells to eliminate aging joint cells, reducing osteoarthritis progression in mice.
A novel class of ferroptosis inhibitors protects donor organs from ischemia-reperfusion injury, potentially saving thousands of transplant patients annually.
A sweeping review maps every known strategy for delivering therapies directly to mitochondria, from lifestyle habits to nanocarriers and gene editing.
A critical review examines the engineering, materials, and biological challenges threatening the long-term reliability of implantable bioelectronic therapies.
Combining nanoparticles with mesenchymal stem cells could finally overcome the poor survival and differentiation that limits cartilage regeneration.