Topic

Alzheimer's

Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline

410 articles

Scientists Restore Memory in Mice by Blocking a Single Alzheimer's Protein
Brain Health

Scientists Restore Memory in Mice by Blocking a Single Alzheimer's Protein

Blocking the protein PTP1B boosted memory and cleared brain plaque in mice, with potential links to diabetes and obesity treatment.

Press Release
May 1, 2026 0
Retracted Alzheimer Study Flagged for Image Manipulation and Data Duplication
Brain Health

Retracted Alzheimer Study Flagged for Image Manipulation and Data Duplication

A 2018 paper on antileukotriene therapy and tau phosphorylation in Alzheimer's mice has been retracted due to image fraud.

Research Paper
May 1, 2026 0
Blood DNA Methylation Score Predicts Cognitive Ability and MCI Risk
Brain Health

Blood DNA Methylation Score Predicts Cognitive Ability and MCI Risk

MethylCog, a 29-CpG blood test, indexes general cognitive ability and improves mild cognitive impairment detection beyond age and sex alone.

Research Paper
May 1, 2026 0
Intranasal Insulin Reverses Memory Loss and Brain Inflammation in Aging Mouse Model
Brain Health

Intranasal Insulin Reverses Memory Loss and Brain Inflammation in Aging Mouse Model

A 9-day intranasal insulin regimen restored working memory, recognition memory, and reduced neuroinflammation in mice engineered to mimic hippocampal aging.

Research Paper
Apr 30, 2026 0
Amyloid Immunotherapy for Alzheimer's Faces a Critical Interpretation Problem
Brain Health

Amyloid Immunotherapy for Alzheimer's Faces a Critical Interpretation Problem

Leading neurologists argue that amyloid aggregation dynamics may be distorting how we read clinical trial results for Alzheimer's immunotherapies.

Research Paper
Apr 30, 2026 0
AI Algorithm Uncovers Distinct Alzheimer's Subtypes Hidden in Brain Omics Data
Brain Health

AI Algorithm Uncovers Distinct Alzheimer's Subtypes Hidden in Brain Omics Data

A multi-omics subspace-merging algorithm identifies biologically distinct AD subtypes, pointing toward personalized treatment strategies.

Research Paper
Apr 30, 2026 0
Scientists Discover Brain Switch That Controls Access to Old vs New Memories
Brain Health

Scientists Discover Brain Switch That Controls Access to Old vs New Memories

A newly identified GABAergic pathway in mice lets the brain toggle between updated and previous memories — a key insight for memory disorders.

Research Paper
Apr 30, 2026 0
MIT Pencil Beam Laser Images Blood-Brain Barrier 25x Faster Than Current Methods
Brain Health

MIT Pencil Beam Laser Images Blood-Brain Barrier 25x Faster Than Current Methods

MIT's self-organizing laser creates ultra-sharp brain images 25x faster, enabling real-time tracking of drugs crossing the blood-brain barrier.

Press Release
Apr 29, 2026 0
Alpha-Synuclein Biomarkers Could Transform Early Parkinson's Diagnosis
Brain Health

Alpha-Synuclein Biomarkers Could Transform Early Parkinson's Diagnosis

New review maps how α-synuclein assays may detect Parkinson's before symptoms appear — and what stands between lab and clinic.

Research Paper
Apr 29, 2026 0
Why Alzheimer's and Parkinson's Share a Protein Misfolding Network
Brain Health

Why Alzheimer's and Parkinson's Share a Protein Misfolding Network

A landmark review argues neurodegeneration is driven by interacting misfolded proteins, not single culprits — reshaping diagnosis and treatment.

Review
Apr 29, 2026 0
Mitochondria-Nucleus Communication Breakdown May Drive Alzheimer's Before Plaques Form
Brain Health

Mitochondria-Nucleus Communication Breakdown May Drive Alzheimer's Before Plaques Form

A new review reveals that disrupted mito-nuclear signaling may precede amyloid and tau pathology, opening fresh therapeutic targets for Alzheimer's.

Research Paper
Apr 29, 2026 0
Poor Arm Blood Flow Predicts Alzheimer's Risk 17 Years Later
Brain Health

Poor Arm Blood Flow Predicts Alzheimer's Risk 17 Years Later

A Framingham study of 2,844 adults links impaired endothelial function to higher Alzheimer's risk, brain shrinkage, and white matter damage.

Research Paper
Apr 29, 2026 0
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