Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
410 articles
New research reveals that the molecular state of immature neurons in the aged hippocampus predicts cognitive resilience — not just their number.
A Phase II trial tests whether blocking herpes virus activity can protect against Alzheimer's disease in early cognitive decline.
A structured neuroplasticity-based program improved functional performance and emotional well-being in community-dwelling older adults with dementia.
Losing a key cholinergic peptide dramatically worsens memory in Alzheimer's mice, pointing to a overlooked pathway in cognitive decline.
New research shows tau pathology disrupts neuronal cargo transport before tangles form — and a kinase inhibitor can reverse it.
Prolonged sleep duration and later wake times predict faster cognitive decline, especially in older adults with amyloid and tau buildup.
A lab study finds ACU193 binds less to brain blood vessels than lecanemab, potentially explaining differences in ARIA side effect risk.
A narrative review reveals India's unique dementia risk profile — and why Western findings may not apply to 1.4 billion people.
In CADASIL patients, MRI-derived brain age runs years ahead of chronological age, tracking disease severity and cognitive decline.
A 12-month Emory trial tests partnered rhythmic dance vs. walking to protect motor-cognitive function in prodromal Alzheimer's patients.
A pilot trial tests whether group and phone-based CBT can sharpen cognition and cut chronic stress in African Americans at risk for Alzheimer's.
A VA-sponsored trial tested whether the blood pressure drug prazosin could remove toxic proteins linked to CTE and Alzheimer's in combat veterans.
