Alzheimer's disease research, amyloid plaques, tau tangles, and cognitive decline
301 articles
Recent NIA findings spotlight lifestyle factors cutting Alzheimer's risk by 60%, calorie restriction slowing aging, and a gene regulating plaque toxicity.
Master the molecular architecture of glymphatic and meningeal lymphatic systems — from AQP4 gating mechanisms to VEGF-C therapy — and explore the cutting-edge interventions targeting these pathways for neurodegeneration prevention.
The National Institute on Aging outlines recent priorities in aging and Alzheimer's disease research, including budget planning and training initiatives.
A Cochrane meta-analysis of 17 RCTs finds amyloid-targeting antibodies offer minimal cognitive gains while significantly raising ARIA risk.
A 10-year Swiss cohort study finds chronic subdural hematoma surgery patients suffer sustained excess mortality and significant cognitive and functional impairments.
First 6-month RCT shows PAP therapy meaningfully improves MoCA scores and motor function in Parkinson's patients with OSA.
New JAMA Neurology analysis reveals that chronic subdural hematoma carries significant long-term neurological effects that extend far beyond the risk of bleeding recurrence.
Stanford researchers find pioglitazone and liraglutide improve CNS insulin signaling, measured via neuron-derived vesicles in blood.
New research reveals how amyloid-β triggers a calcium-cholesterol cascade in brain cells that clogs the glymphatic system — and how statins may reverse it.
Go beyond the basics and explore the molecular machinery behind glymphatic flow, AQP4 water channels, meningeal lymphatics, and why their dysfunction drives neurodegeneration.
Discover how your brain flushes out toxic waste while you sleep — and why this nightly cleanup is one of the most important things you can do for long-term brain health.
Large European study of 10,000+ older adults reveals loneliness impacts baseline memory but doesn't speed up mental decline over time.
