Autoimmune diseases, immune modulation, inflammation, and self-tolerance
169 articles
New research reveals how helper T cells become highly destructive in joints, offering potential therapeutic targets for autoimmune arthritis.
Scientists discover how immune cells work together in unexpected ways, opening new paths for cancer therapy and transplant success.
Mitochondrial complex II in intestinal cells regulates T cell immune responses and inflammation pathways.
Researchers analyzed over 1 million brain cells to create the first comprehensive map of microglia across diseases.
New research reveals how immune cells in tumors can both fight and fuel cancer growth, opening paths to better therapies.
New research reveals how removing ZFP148 protein boosts CD8+ T cells' cancer-fighting ability and improves immunotherapy response.
New research reveals how our body clock regulates immune cell function through DNA modifications, offering insights for health optimization.
Discover how persistent low-grade inflammation drives the aging process and learn strategies to combat this silent threat to longevity.
Phase I trial tests selective JAK3 inhibitor with improved safety profile compared to existing treatments for inflammatory conditions.
Small NIH study tests oral drug tofacitinib as potential new treatment for systemic lupus erythematosus with fewer side effects.
Small study tests whether tocilizumab can achieve faster, deeper remission in newly diagnosed rheumatoid arthritis patients.
Phase 2 trial tests novel therapy for patients who failed standard biologics and JAK inhibitors in 145-person study.
