Cancer Research
Rogue Cell State Fuels Colorectal Cancer Spread — and a Drug Can Reverse It
A high-MAPK, low-WNT tumor cell state drives CRC metastasis, and blocking mutant KRAS suppresses it in mice.
Research Paper
May 8, 2026 0
Topic
Cancer
Latest breakthroughs in cancer research, treatment, and prevention
648 articles
Cancer Research
9-Week Immunotherapy Before Surgery Keeps Colon Cancer Patients Relapse-Free for 3 Years
A short pre-surgery course of pembrolizumab left zero relapses in colorectal cancer patients after 33 months — reshaping treatment strategy.
Press Release
May 7, 2026 0
Cancer Research
Senolytics Fail to Protect Bone From Chemotherapy-Induced Loss
A mouse study finds that senolytic drugs cannot prevent chemotherapy-driven bone loss, challenging a leading hypothesis about its cause.
Research Paper
May 7, 2026 0
Cancer Research
Ferroptosis Emerges as a Targetable Vulnerability in Deadly Anaplastic Thyroid Cancer
A comprehensive review reveals how iron-driven cell death can be exploited to treat ATC, one of the most lethal human cancers.
Research Paper
May 7, 2026 0
Cancer Research
HDAC Inhibitor Plus Checkpoint Blocker Tested in Advanced Lung Cancer Trial
A phase 1/2 trial combined mocetinostat and durvalumab in 83 patients with advanced solid tumors and NSCLC.
Clinical Trial
May 7, 2026 0
Cancer Research
Low-Dose Ipilimumab Plus Pembrolizumab Targets Melanoma Brain Metastases
A completed Phase II trial tests whether combining two checkpoint inhibitors can safely and effectively treat melanoma that has spread to the brain.
Clinical Trial
May 7, 2026 0
Cancer Research
Nivolumab Patient Develops Rare Brain-to-Blood Bacterial Spread from Oral Microbe
A cancer patient on nivolumab developed Eikenella corrodens bacteremia after CNS infection, revealing how immune checkpoint therapy may enable dangerous microbial dissemination.
Research Paper
May 6, 2026 0
Cancer Research
FDA Grants Expanded Approval to Zongertinib for HER2-Mutant Lung Cancer
The FDA expanded accelerated approval for zongertinib in HER2-mutant NSCLC, marking a targeted therapy milestone for a hard-to-treat mutation.
Drug Approval
May 6, 2026 0
Cancer Research
Stiff Breast Tissue Recruits Immune Cells That Damage DNA and Drive Cancer
Tissue stiffness triggers a chain reaction — recruiting macrophages that generate DNA-damaging lipid byproducts — linking fibrosis directly to cancer initiation.
Research Paper
May 6, 2026 0
Cancer Research
IL-6 Signaling Exposes a Metabolic Weak Spot in Bile Duct Cancer
Tumor cells in intrahepatic cholangiocarcinoma hijack IL-6 signaling to fuel growth — creating a targetable metabolic vulnerability.
Research Paper
May 5, 2026 0
Cancer Research
New c-Met Antibody-Drug Conjugate Shows Promise in Late-Stage Colorectal Cancer
Phase I trial of Temab-A reports 15.6% response rate and 74.6% disease control in heavily pretreated metastatic colorectal cancer patients.
Research Paper
May 3, 2026 0
Cancer Research
T Cell Vesicles Deliver DNA to Boost Anti-Tumor Immunity
Activated T cells release vesicles carrying genomic DNA that reprogram recipient cells to display tumor antigens more effectively.
Research Paper
May 2, 2026 0