A New Framework for Targeting Cancer's Hidden Ally: Tumor Fibroblasts
Researchers propose a unified model classifying cancer-associated fibroblasts by molecular phenotype and spatial location to guide precision therapy.
Latest breakthroughs in cancer research, treatment, and prevention
643 articles
Researchers propose a unified model classifying cancer-associated fibroblasts by molecular phenotype and spatial location to guide precision therapy.
Corticosterone triggered by gut microbiome-derived phage DNA disables B cell tumor immunity, revealing a stress-cancer axis.
A phase I trial tests SD-101, nivolumab, and radiation together against metastatic pancreatic cancer that has stopped responding to chemo.
A new study finds elevated LDL, total cholesterol, and triglycerides significantly raise colorectal adenoma risk — a key cancer precursor.
A Chinese cohort study reveals the cancer risk landscape for patients with autoimmune gastritis, a condition frequently underdiagnosed in Asian populations.
Spatial-EV-seq charts where cancer-shielding vesicles cluster in tissue, exposing why immunotherapy fails in some tumor zones.
A sex-specific GABA signaling pathway supercharges immune suppression in female glioblastoma, revealing a potential new immunotherapy target.
A Phase 1/2 trial tests a custom cancer vaccine paired with checkpoint inhibitors in patients with advanced solid tumors.
The FDA has greenlighted a new active sunscreen ingredient, the first approval of its kind in years, expanding UV protection options.
A newly discovered phage-fibroblast-B cell circuit explains how chronic stress drives tumor growth by suppressing anti-tumor immunity.
Researchers discovered why fibrolamellar carcinoma resists immunotherapy and found an existing drug can free trapped T cells to fight it.
A completed phase 3 trial compared A+AVD versus ABVD for advanced classical Hodgkin lymphoma, testing whether replacing bleomycin with brentuximab vedotin improves outcomes.